# Complete genome sequence of three atypical diarrheagenic Escherichia coli O166:H15 strains from foodborne outbreaks

**Authors:** Akiko Kubomura, Kenichi Lee, Sunao Iyoda, Yukihiro Akeda

PMC · DOI: 10.1128/mra.00746-25 · Microbiology Resource Announcements · 2025-10-09

## TL;DR

This paper reports the complete genome sequences of three unusual Escherichia coli O166:H15 strains linked to foodborne outbreaks in Japan.

## Contribution

The study provides new genomic insights into atypical E. coli strains lacking common virulence factors.

## Key findings

- The genome sequences of three E. coli O166:H15 isolates were fully characterized.
- These strains were found to lack typical virulence factors seen in diarrheagenic E. coli.
- The findings contribute to understanding the genomic basis of these atypical strains.

## Abstract

Escherichia coli O166:H15 strains have been repeatedly isolated from foodborne outbreaks in Japan. These strains lack the major virulence factors typically associated with diarrheagenic E. coli. To characterize the genomic features of these atypical strains, we present the complete genome sequences of three E. coli O166:H15 isolates from foodborne outbreaks.

## Linked entities

- **Diseases:** diarrhea (MONDO:0001673)
- **Species:** Escherichia coli (taxon 562), Escherichia coli O166:H15 (taxon 2802033)

## Full-text entities

- **Species:** Escherichia coli (E. coli, species) [taxon 562]

## Full text

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12613895/full.md

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Source: https://tomesphere.com/paper/PMC12613895