# Complete genome sequence of Rothia mucilaginosa D1, a genetically amenable strain

**Authors:** Hemendra P.S. Dhaked, Isabella Andonie, Bo Yang, Vinayka M. Joshi, Zezhang T. Wen

PMC · DOI: 10.1128/mra.00564-25 · Microbiology Resource Announcements · 2025-09-23

## TL;DR

The complete genome of Rothia mucilaginosa D1, a strain useful for genetic studies, has been sequenced.

## Contribution

This is the first complete genome sequence of a genetically amenable clinical isolate of Rothia mucilaginosa.

## Key findings

- The genome sequence of R. mucilaginosa D1 is now available for further research.
- This strain is genetically amenable, making it suitable for experimental studies.
- The sequencing supports investigations into the pathophysiology of this emerging pathobiont.

## Abstract

Here, we report the complete genome sequence of Rothia mucilaginosa D1. Unlike many other strains that have been sequenced, R. mucilaginosa D1, a clinical isolate, is genetically amenable. The complete sequencing of the genome provides potential for further studies on the genetics and pathophysiology of this emerging pathobiont.

## Linked entities

- **Species:** Rothia mucilaginosa (taxon 43675)

## Full-text entities

- **Diseases:** endodontitis (MESH:D011671), dental caries (MESH:D003731), candidiasis (MESH:D002177), acute and chronic diseases (MESH:D000208), pneumonia (MESH:D011014)
- **Chemicals:** glucose (MESH:D005947), beta-glucoside (-), fructose (MESH:D005632), lactose (MESH:D007785), NAD (MESH:D009243), mannose (MESH:D008358)
- **Species:** Rothia mucilaginosa (species) [taxon 43675], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12613889/full.md

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Source: https://tomesphere.com/paper/PMC12613889