# Altered proteome of a cystic fibrosis cell line model upon exposure to Pseudomonas aeruginosa biofilms

## TL;DR

This study examines how a cystic fibrosis cell line's protein levels change when exposed to bacterial biofilms.

## Contribution

The novelty lies in analyzing proteome alterations in a cystic fibrosis model due to Pseudomonas aeruginosa biofilms.

## Key findings

- Exposure to Pseudomonas aeruginosa biofilms alters proteome regulation in cystic fibrosis cells.
- The study identifies specific protein changes linked to bacterial invasion in cystic fibrosis.

## Abstract

Cystic fibrosis is associated with disruption of a key ion channel responsible for maintaining lung health. Upon disruption, fluids build within the lungs, creating a favorable environment for bacterial invasion. In this study, we assessed altered proteome regulation of a cystic fibrosis cell line model in response to bacterial biofilms.