# Complete genome sequence of Streptococcus oralis subsp. tigurinus J22, a model strain for antagonistic interaction against Streptococcus mutans

**Authors:** Hee-Young Jung, Jina-Na Cai, Dongyeop Kim

PMC · DOI: 10.1128/mra.00677-25 · Microbiology Resource Announcements · 2025-10-24

## TL;DR

This paper reports the complete genome sequence of a bacteria that can fight tooth decay-causing microbes.

## Contribution

The study provides the complete genome sequence of Streptococcus oralis subsp. tigurinus J22, a model for antagonistic interactions.

## Key findings

- The genome of S. oralis subsp. tigurinus J22 is 1,967,320 bp with 41.1% GC content.
- The strain produces hydrogen peroxide and antagonizes Streptococcus mutans.
- It serves as a model for studying microbial antagonism in the oral cavity.

## Abstract

Streptococcus oralis subsp. tigurinus strain J22, a potent hydrogen peroxide-producing oral commensal. Given the antagonistic action against a cariogenic pathogen, this strain can be used as a model bacterium to characterize microbial antagonistic interactions. S. oralis J22 has a genome sequence of 1,967,320 bp along with 41.1% GC content.

## Linked entities

- **Species:** Streptococcus oralis subsp. tigurinus (taxon 1077464), Streptococcus mutans (taxon 1309)

## Full-text entities

- **Chemicals:** J22 (-), hydrogen peroxide (MESH:D006861)
- **Species:** Streptococcus mutans (species) [taxon 1309], Streptococcus oralis (species) [taxon 1303]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12613867/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12613867/full.md

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Source: https://tomesphere.com/paper/PMC12613867