# Antimicrobial resistance profiles of Campylobacter spp. isolated from retail meat in Puerto Rico

**Authors:** Gustavo Quiñones Justiniano, Esther M. Vega Quiñones, Edward G. Dudley, Nkuchia M. M'ikanatha, Yadira Malavez

PMC · DOI: 10.1128/mra.00821-25 · Microbiology Resource Announcements · 2025-09-30

## TL;DR

This study analyzed antibiotic resistance in Campylobacter bacteria from retail meat in Puerto Rico, finding multiple drug resistances linked to specific genetic factors.

## Contribution

The study identifies specific genetic markers associated with multidrug resistance in Puerto Rican retail meat Campylobacter isolates.

## Key findings

- Resistance to tetracycline, ciprofloxacin, clindamycin, and florfenicol was observed in isolates.
- Multidrug resistance was linked to the presence of tet(O), gyrA mutations, and cmeABC.
- The findings highlight the public health risk of antimicrobial-resistant Campylobacter in retail meat.

## Abstract

Whole-genome sequencing and antimicrobial susceptibility testing were performed on 29 Campylobacter isolates from retail meat in Puerto Rico. Resistance to tetracycline, ciprofloxacin, clindamycin, and florfenicol was observed. Multidrug resistance was linked to co-occurrence of tet(O), gyrA mutations, and cmeABC, highlighting the public health risk of antimicrobial-resistant Campylobacter in retail meat.

## Linked entities

- **Genes:** tet(O) (tetracycline resistance ribosomal protection protein Tet(O)) [NCBI Gene 8154417], GYRA (DNA GYRASE A) [NCBI Gene 820238]
- **Chemicals:** tetracycline (PubChem CID 54675776), ciprofloxacin (PubChem CID 2764), clindamycin (PubChem CID 446598), florfenicol (PubChem CID 114811)

## Full-text entities

- **Chemicals:** florfenicol (MESH:C035534), ciprofloxacin (MESH:D002939), tetracycline (MESH:D013752), clindamycin (MESH:D002981)
- **Species:** Campylobacter (genus) [taxon 194]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12613857/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12613857/full.md

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Source: https://tomesphere.com/paper/PMC12613857