# Enhanced Electrochemical Sensing of Treprostinil: A Novel Approach for Sensitive and Selective Detection

## TL;DR

A new electrochemical sensor for detecting the drug treprostinil offers high sensitivity and selectivity, useful for medical and pharmaceutical purposes.

## Contribution

A novel NiPB@Cu/Cu2O/GCE electrochemical sensor for sensitive and selective detection of treprostinil is developed.

## Key findings

- The sensor shows excellent sensitivity and selectivity for treprostinil detection.
- The sensor has a wide linear range and low detection limit.
- The nanomaterial was characterized using FE-SEM, STEM, XRD, and FTIR.

## Abstract

Treprostinil (TRP) is a potent vasodilator used in the
treatment
of pulmonary arterial hypertension (PAH). The development of a rapid,
sensitive, and selective electrochemical detection method for TRP
is crucial for therapeutic monitoring and quality control. In this
study, we present a novel electrochemical sensor for TRP based on
NiPB@Cu/Cu2O/GCE. The NiPB@Cu/Cu2O/GCE sensor
exhibits excellent sensitivity and selectivity, enabling reliable
quantification of TRP in biological and pharmaceutical samples. The
nanomaterial used in the sensor was characterized using field emission
scanning electron microscopy (FE-SEM), scanning transmission electron
microscopy (STEM), X-ray diffraction (XRD), and Fourier transform
infrared spectroscopy (FTIR) to confirm its structural and morphological
properties. The developed sensor demonstrated a wide linear range,
low detection limit, and high reproducibility, making it a promising
tool for clinical and pharmaceutical applications. This study provides
a significant advancement in the electrochemical analysis of TRP,
paving the way for further applications in drug monitoring and biomedical
research.