# Hypokalemic Periodic Paralysis: A Case Report

**Authors:** Mohsin Wani, Zara Marchant, Umed Nadir

PMC · DOI: 10.7759/cureus.94524 · Cureus · 2025-10-14

## TL;DR

A 17-year-old male with hypokalemic periodic paralysis showed acute muscle weakness and low potassium, resolving after treatment.

## Contribution

This case emphasizes the importance of diagnosing HPP in young patients with acute muscle weakness and hypokalaemia.

## Key findings

- Acute limb weakness in a 17-year-old male was linked to hypokalaemia (2.7 mmol/L).
- Symptoms resolved after intravenous potassium replacement.
- HPP should be considered in young patients with acute muscle weakness and low potassium.

## Abstract

Hypokalaemic periodic paralysis (HPP) is a rare neuromuscular disorder characterized by recurrent episodes of transient muscle weakness associated with hypokalaemia. The condition typically presents in childhood or adolescence.

In this case, a 17-year-old male presented with acute-onset limb weakness upon waking. Examination revealed marked truncal and proximal muscle weakness with preserved distal strength. Serum potassium was 2.7 mmol/L. His symptoms fully resolved following intravenous potassium replacement.

HPP is often underdiagnosed, and diagnostic delays can leave patients vulnerable to avoidable complications, including recurrent episodes and potentially life-threatening arrhythmias. This case highlights the importance of considering HPP in young patients presenting with acute muscle weakness and hypokalaemia.

## Full-text entities

- **Diseases:** limb weakness (MESH:D018908), neuromuscular disorder (MESH:D009468), arrhythmias (MESH:D001145), HPP (MESH:D010245)
- **Chemicals:** potassium (MESH:D011188)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12612784/full.md

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Source: https://tomesphere.com/paper/PMC12612784