# Reliability of artificial intelligence algorithms in automated age estimation using orthopantomograms: A scoping review

**Authors:** Spoorti Kulkarni, Sudeendra Prabhu, Andrew Jeyabose, Vikram Palimar

PMC · DOI: 10.1177/20552076251390556 · Digital Health · 2025-11-12

## TL;DR

This study reviews AI algorithms for estimating age from dental X-rays, finding they are more accurate than traditional methods and could aid forensic and clinical work.

## Contribution

The study systematically evaluates AI models for age estimation from orthopantomograms, highlighting their reliability and potential clinical impact.

## Key findings

- AI models like CNNs and EfficientNet show higher accuracy than traditional age estimation methods.
- AI-driven age estimation reduces human error and enhances decision-making in forensic and clinical settings.
- Standardized protocols are needed to integrate AI models into forensic odontology practices.

## Abstract

This study aims to evaluate the efficiency of AI (artificial intelligence) algorithms for automated age estimation using orthopantomograms (OPGs) and to determine whether these models can effectively replace conventional age estimation techniques.

Three independent literature searches were conducted in PubMed, Scopus, and Embase. Studies published in the English language were considered, focusing on age estimation using AI. A total of 1519 articles were screened, and 24 articles were included in the study. The data was extracted in a standardized, predefined manner. After finalizing the search, the data collected was tabulated, interpreted, and verified. The selected studies were analyzed for methodological rigor, algorithmic performance, and comparative effectiveness against traditional age estimation methods.

AI-based models, especially deep learning architectures like convolutional neural networks, EfficientNet, DenseNet, and hybrid models such as Age-Net, demonstrated superior accuracy, precision, and reliability compared to traditional age estimation methods. These AI-driven models show promising results in reducing human error, increasing efficiency, and enhancing forensic and clinical decision-making.

AI-driven age estimation using OPGs represents a transformative advancement with considerable forensic and clinical potential. Although these AI models may not yet fully replace conventional techniques, they offer a substantial value as complementary tools, improving both accuracy and operational efficiency. To foster wider adoption and improve reliability, ongoing research and the development of standardized protocols are essential for integrating these methods into forensic odontology and related fields.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12612522/full.md

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Source: https://tomesphere.com/paper/PMC12612522