# Effects of group hypnotic intervention on pregnant mental health and delivery mode: a retrospective analysis

**Authors:** Xuelian Cui, Wei Chen, Xiaosong Yuan, Huiwen Hu, Zhiwei Liu

PMC · DOI: 10.3389/fmed.2025.1671398 · Frontiers in Medicine · 2025-10-30

## TL;DR

Group hypnotic sessions during pregnancy reduced depression and anxiety symptoms and increased vaginal delivery rates compared to standard care.

## Contribution

This study demonstrates the effectiveness of group hypnotic intervention in improving mental health and delivery outcomes in pregnant women.

## Key findings

- Group hypnotic intervention led to sustained improvement in depression and anxiety symptoms from pre-intervention to 38 weeks' gestation.
- The intervention group had significantly greater reductions in HADS, HAMD, and HAMA scores compared to controls.
- Vaginal delivery rates were significantly higher in the intervention group.

## Abstract

Depression and anxiety are highly prevalent during pregnancy, with psychological interventions being recommended as the first-line treatment.

This study examined the effects of group hypnotic intervention on prenatal depression, anxiety symptoms, and delivery mode.

In a single-center retrospective observational design, 237 pregnant women were included. The intervention group received group hypnotic sessions, while the control group received standard prenatal care. Baseline sociodemographic and clinical characteristics were recorded, including scores on the Hospital Anxiety and Depression Scale (HADS), Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), and heart rate variability (low-frequency/high-frequency ratio [LF/HF]). Measurements were collected at three gestational timepoints (pre-intervention, post-intervention, and 38 weeks’ gestation). Between-group and within-group differences in symptom scores and LF/HF were analyzed, and a logistic regression analysis assessed the association between the intervention and the delivery mode.

Within-group analyses demonstrated sustained improvement in depression/anxiety symptoms (p < 0.001) and increased LF/HF ratio (p < 0.001) in the intervention group from pre-intervention to 38 weeks’ gestation. In contrast, the control group exhibited reduced HADS, HAMD, and HAMA scores at post-intervention (vs. pre-intervention; p = 0.002–0.003), but returned to baseline levels at 38 weeks’ gestation (vs. pre-intervention, p = 0.083–0.216). Between-group comparisons revealed significantly greater reductions in HADS, HAMD, and HAMA scores across all time points in the intervention group vs. controls (p < 0.001 for all). Vaginal delivery rates were also significantly higher in the intervention group (p = 0.04).

Group hypnotic intervention effectively alleviated prenatal depression and anxiety symptoms and improved vaginal delivery outcomes, suggesting its integration into routine prenatal mental healthcare protocols.

## Linked entities

- **Diseases:** depression (MONDO:0002050), anxiety (MONDO:0005618)

## Full-text entities

- **Diseases:** Depression (MESH:D003866), Anxiety (MESH:D001007)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

35 references — full list in the complete paper: https://tomesphere.com/paper/PMC12611927/full.md

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Source: https://tomesphere.com/paper/PMC12611927