# The herbal pharmacopoeia of Ecuador: a national model for integrating traditional knowledge and biodiscovery

**Authors:** Susana Llivisaca-Contreras, Jaime Naranjo-Morán, Martín Bastidas-Gálvez, Jairo Jaime-Carvajal, María Muenala-Tituaña, Patricia Manzano-Santana, Adrián Abad-Mihalache, Andrea Abril-Novillo, Juan M. Cevallos-Cevallos, Andrea Orellana-Manzano, Fabián León-Tamariz

PMC · DOI: 10.3389/fphar.2025.1662980 · Frontiers in Pharmacology · 2025-10-30

## TL;DR

Ecuador is creating a scientific herbal pharmacopoeia to organize traditional and scientific knowledge on medicinal plants, promoting safe use and biodiversity conservation.

## Contribution

The paper introduces a national herbal pharmacopoeia model integrating traditional knowledge and scientific validation in Ecuador.

## Key findings

- A digital platform was developed to systematize information on 14 medicinal plants through interdisciplinary monographs.
- The pharmacopoeia supports regulation of natural products and protects ancestral knowledge in Ecuador.
- Collaboration among government, academia, and communities is critical for the pharmacopoeia's success.

## Abstract

The Herbal Pharmacopoeia of Ecuador is a proposal aimed at systematizing and organizing information on the use of medicinal plants and natural products through the scientific evaluation of existing knowledge (ancestral or otherwise) in Ecuador, a country with high biodiversity and a rich ethnobotanical heritage, contributing to the safe use of medicinal plants and their potential phytopharmaceutical derivatives, offering safe alternatives for the treatment or relief of various health conditions.

To build a foundation that organizes and structures validated information on medicinal plants and natural products, serving in the future as a reference resource for the development of phytotherapeutic products, knowledge transfer, protection of ancestral knowledge, supported by regulatory bodies, and as a source of consultation for health professionals in Ecuador.

An interdisciplinary approach was used to develop monographs on medicinal plants used in various regions of Ecuador, integrating an extensive literature review that highlights ethnobotanical, pharmacological, and phytochemical analysis. In a collaborative effort by academic institutions integrated into the VLIR-Ecuador Network, a digital platform was developed using the Angular software framework to organize these monographs.

The creation of a digital platform enabled the systematization of scientific knowledge on 14 selected medicinal plants through the generation of monographs, organized within the Ecuadorian Herbal Pharmacopoeia. This has facilitated access for the medical and scientific community to relevant data on the common use of plants and traditional Ecuadorian medicine.

The official adoption of an Herbal Pharmacopoeia in Ecuador will strengthen scientific production, support the regulation of natural products, protect ancestral knowledge, and promote research on bioactive compounds. Its success will depend on collaboration between the government, academia, industry, and ancestral communities, ensuring its development and positioning Ecuador as a leading reference in ethnobotany and biosustainability.

## Full-text entities

- **Diseases:** Fever (MESH:D005334), colic (MESH:D003085), myiasis (MESH:D009198), diarrhea (MESH:D003967), cancer (MESH:D009369), muscle (MESH:D019042), infectious diseases (MESH:D003141), measles (MESH:D008457), COVID-19 (MESH:D000086382), rheumatism (MESH:D012216), ulcers (MESH:D014456), toxicities (MESH:D064420), hypertension (MESH:D006973)
- **Species:** Artemisia annua (sweet Annie, species) [taxon 35608], Theobroma cacao (cacao, species) [taxon 3641], Azadirachta indica (Indian-lilac, species) [taxon 124943], Lucilia (genus) [taxon 90969], Passiflora edulis f. flavicarpa (forma) [taxon 237848], Conyza bonariensis (species) [taxon 91242], Mansoa alliacea (species) [taxon 353996], Methanosarcina mazei (species) [taxon 2209], Clinopodium nubigenum (species) [taxon 332442], Peperomia galioides (species) [taxon 352177], Homo sapiens (human, species) [taxon 9606], Minthostachys mollis (species) [taxon 260606], Arabidopsis thaliana (mouse-ear cress, species) [taxon 3702]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12611923/full.md

## References

97 references — full list in the complete paper: https://tomesphere.com/paper/PMC12611923/full.md

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Source: https://tomesphere.com/paper/PMC12611923