# If Tregs were people: regulation as the quiet architecture of immunity and society

**Authors:** Bruno B. Andrade, Mariana Araújo-Pereira

PMC · DOI: 10.3389/fimmu.2025.1720091 · Frontiers in Immunology · 2025-10-30

## Full-text entities

- **Genes:** IL2 (interleukin 2) [NCBI Gene 3558] {aka IL-2, TCGF, lymphokine}, CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}, CTLA4 (cytotoxic T-lymphocyte associated protein 4) [NCBI Gene 1493] {aka ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4}, TGFB1 (transforming growth factor beta 1) [NCBI Gene 7040] {aka CAEND1, CED, DPD1, IBDIMDE, LAP, TGF-beta1}, CXADRP1 (CXADR pseudogene 1) [NCBI Gene 653108] {aka CAR, CXADRP}, FOXP3 (forkhead box P3) [NCBI Gene 50943] {aka AIID, DIETER, IPEX, JM2, PIDX, XPID}, IL2RA (interleukin 2 receptor subunit alpha) [NCBI Gene 3559] {aka CD25, IDDM10, IL2R, IMD41, TCGFR, p55}, IL10 (interleukin 10) [NCBI Gene 3586] {aka CSIF, GVHDS, IL-10, IL10A, TGIF}
- **Diseases:** colitis (MESH:D003092), myocarditis (MESH:D009205), chronic graft-versus-host disease (MESH:D000092122), thyroiditis (MESH:D013966), fever (MESH:D005334), inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12611679/full.md

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Source: https://tomesphere.com/paper/PMC12611679