# Impact of active tuberculosis on social mobility and its gender differences: Difference in differences using nationwide tuberculosis surveillance data and national health insurance data

**Authors:** Daseul Moon, Dawoon Jeong, Young Ae Kang, Gyeong In Lee, Hongjo Choi

PMC · DOI: 10.1371/journal.pone.0334961 · PLOS One · 2025-11-12

## TL;DR

This study finds that active tuberculosis leads to long-term income decline in men but not in women, highlighting gender differences in social mobility.

## Contribution

The study uses nationwide data and a difference-in-differences model to reveal gender-specific impacts of TB on income.

## Key findings

- Men with active TB experienced a significant decline in household income over time.
- Women with active TB did not show a marked income decline, but subgroups showed some trends.
- Gender roles in a patriarchal society may explain differences in income outcomes after TB diagnosis.

## Abstract

Although reducing catastrophic total costs caused by TB is a major public health concern, there is a scarcity of long-term follow-up studies on social suffering due to TB as well as studies examining gender gaps. This study aims to examine the degree of long-term change in household incomes due to active TB by gender. We created data for the TB and control groups by linking the Korean National Tuberculosis Surveillance System (KNTSS) and National Health Information Database (NHID) and covariate-adjusted propensity score matching (PSM). We created longitudinal panel data from two years before TB diagnosis (t) to two years after TB diagnosis and analyzed the changes in household income deciles by gender and group using a difference in differences (DID) model. In men, there was a clear trend of declining income since time t in the TB group (DID coefficient = −0.131 95% CI = −0.132 ~ −0.129), but there was no marked change in women. Subgroup analyses on the working-age population (20–65 years) (DID coefficient = −0.053, 95% CI = −0.096 ~ −0.010) and employee population (DID coefficient = −0.072, 95% CI = −0.110 ~ −0.034) showed a trend of declining income in the female TB group. This study showed that there is a marked trend of declining income due to the diagnosis and treatment of active TB in men but not in women. This discrepancy may be attributable to the differences in gender roles in a patriarchal society and higher possibility of women moving out of the labor market after disease. There is a pressing need for comprehensive and universal implementation of health and social protection policies to alleviate the trend of social suffering caused by disease.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** active (OMIM:612348), Tuberculosis (MESH:D014376), TB (MESH:D014390)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12611136/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12611136/full.md

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Source: https://tomesphere.com/paper/PMC12611136