# Non-operative management of barium peritonitis: a case report

**Authors:** Muhammad Mohsin Khan, Abdullah Bin Faisal, Rabia Chang, Usama Iqbal

PMC · DOI: 10.1093/jscr/rjaf633 · 2025-11-12

## TL;DR

A patient with barium peritonitis was successfully treated without surgery, suggesting conservative management can work in stable cases.

## Contribution

This case report presents a rare instance of successful non-surgical treatment of barium peritonitis.

## Key findings

- Conservative management with antibiotics and drainage resolved barium peritonitis without surgery.
- The patient remained stable and asymptomatic during follow-up after conservative treatment.
- The case suggests reconsidering barium-based contrast agents in high-risk patients.

## Abstract

Barium peritonitis is a rare but serious complication caused by leakage of barium sulfate into the peritoneal cavity during gastrointestinal contrast studies. It carries high mortality and often necessitates surgical intervention. A 33-year-old female developed chemical peritonitis following a barium loopogram performed during her ileostomy reversal workup. Imaging revealed pneumoperitoneum and intra-abdominal collections due to barium spillage. Despite radiological findings, she remained clinically stable with only localized symptoms. Conservative management was pursued with intravenous antibiotics, hydration, analgesia, and CT-guided drainage. Surgery was avoided due to her stable clinical status and normal inflammatory markers. She recovered completely without in-hospital complications and remained asymptomatic on follow-up. This case demonstrates that conservative management of barium peritonitis is a viable option in selected stable patients. It also highlights the need to reconsider the use of barium-based contrast agents in favor of safer alternatives, especially in high-risk individuals.

## Linked entities

- **Chemicals:** barium sulfate (PubChem CID 24414)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), peritonitis (MESH:D010538), pneumoperitoneum (MESH:D011027)
- **Chemicals:** barium (MESH:D001464), Barium peritonitis (-), barium sulfate (MESH:D001466)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12610394/full.md

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Source: https://tomesphere.com/paper/PMC12610394