Short-Term Outcomes of Micropulse Transscleral Cyclophotocoagulation Using the VITRA 810 and Postoperative Ciliochoroidal Effusion in Japanese Patients

TL;DR

This study evaluated the short-term effects of a laser treatment for glaucoma in Japanese patients, showing reduced eye pressure and some complications.

Contribution

The study provides new insights into the effectiveness and safety of VITRA 810 MP-TSCPC in Japanese patients.

Findings

Intraocular pressure significantly decreased after treatment at all follow-up intervals.

Ciliochoroidal effusion was observed in nearly 60% of patients and linked to greater early IOP reduction.

Complications included mydriasis, inflammation, and rare severe outcomes like phthisis bulbi.

Abstract

Background: This study aimed to evaluate the short-term outcomes of micropulse transscleral cyclophotocoagulation (MP-TSCPC) using the VITRA 810 in Japanese patients, focusing on intraocular pressure (IOP), medication score, complications, and ciliochoroidal effusion (CE). Methods: We retrospectively reviewed 37 eyes of 34 patients treated between March 2024 and March 2025. Postoperative IOP, glaucoma medication score, complications, and CE assessed by anterior segment OCT were analyzed. IOP changes were compared between CE-positive and CE-negative groups. Results: The mean preoperative IOP was 22.8 ± 7.1 mmHg, which decreased to 13.3 ± 6.8 mmHg at 1 week, 14.9 ± 7.4 mmHg at 1 month, 14.9 ± 5.8 mmHg at 3 months, and 15.0 ± 5.2 mmHg at 6 months (all p < 0.05 vs. baseline). CE was observed in 22 eyes (59.4%) and was associated with greater IOP reduction at 1 week and 1 month. Complications included mydriasis (24.3%), anterior chamber inflammation (24.3%), cystoid macular edema (5.4%), decreased visual acuity (8.1%), and phthisis bulbi (2.7%). Conclusions: VITRA 810 MP-TSCPC achieved significant short-term IOP reduction in Japanese patients. CE was linked to greater early IOP lowering. While generally safe, rare but severe complications such as phthisis bulbi require close monitoring.

Figures