# Mindfulness-Based Stress Reduction Program to Improve Well-Being and Health in Healthcare Professionals

**Authors:** Marco Marotta, Niccolo Grassi, Alessandro Pingitore, Alessandra Parlanti, Sergio Berti, Cristina Vassalle

PMC · DOI: 10.3390/jcm14217655 · 2025-10-28

## TL;DR

This study shows that a mindfulness program can improve mental and physical health in healthcare workers.

## Contribution

The study demonstrates that MBSR can reduce stress and improve lipid profiles in healthcare professionals.

## Key findings

- MBSR significantly improved psychological well-being and reduced stress and burnout in healthcare professionals.
- The program also led to significant improvements in lipid profiles.
- Healthcare professionals showed moderate distress at baseline but improved after the MBSR program.

## Abstract

Aim: To evaluate basal well-being and the effects of a Mindfulness-Based Stress Reduction (MBSR) program in health-care professionals (HCPs), a recognized worker category subjected to elevated stress from job conditions. Methods: A quasi-experimental pre–post study was conducted in Italian HCPs. Well-being (assessed by Psychological General Well-Being Index-PGWBI), stress (Perceived Stress Scale-PSS), and burnout (Maslach Burnout Inventory-MBI) were collected at baseline and after an MBSR program. Moreover, levels of C reactive protein, glucose, and lipid profiles were also monitored in a subgroup. Results: At baseline, Total-PGWBI score value evidenced no distress, whereas Total-PSS and MBI dimensions (emotional exhaustion—EE, depersonalization and detachment from the job—DP, and lack of personal or professional accomplishment—PA) indicate moderate distress. After MBSR, PGWBI, PSS, and MBI dimensions significantly improved. Moreover, significant benefits on lipid profile were observed after MBSR. Conclusions: MBSR may be a promising method to improve well-being and lipid profile in HCPs. Thus, MBSR might represent a new future complementary prevention tool for mental and physical health maintenance in this category of workers.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** Burnout (MESH:D002055)
- **Chemicals:** lipid (MESH:D008055), glucose (MESH:D005947)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12610075/full.md

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Source: https://tomesphere.com/paper/PMC12610075