# Validity of a Convolutional Neural Network-Based, Markerless Pose Estimation System Compared to a Marker-Based 3D Motion Analysis System for Gait Assessment—A Pilot Study

**Authors:** Korbinian Ksoll, Rafael Krätschmer, Fabian Stöcker

PMC · DOI: 10.3390/s25216551 · 2025-10-24

## TL;DR

This pilot study compares a markerless gait analysis system using CNNs to a traditional marker-based system and finds it effective for most gait metrics.

## Contribution

The study validates a CNN-based markerless gait analysis system as a viable alternative to traditional marker-based systems.

## Key findings

- The CNN-based system showed strong to almost complete agreement with marker-based systems for most sagittal and frontal plane gait metrics.
- Gait symmetry showed only moderate to weak correlation between the two systems.
- The markerless system is proposed as a suitable alternative for clinical gait assessment.

## Abstract

Gait analysis is a valuable tool for a wide range of clinical applications. Until now, the standard for gait analysis has been marker-based 3D optical systems. Recently, markerless gait analysis systems that utilize pose estimation models based on Convolutional Neural Networks (CNNs) and computer vision have gained importance. In this pilot study, we validated the performance of a CNN-based, markerless pose estimation algorithm (Orthelligent® VISION; OV) compared to a standard marker-based 3D motion capture system in 16 healthy adults. Standard gait metrics were analyzed by calculating concordance correlation coefficients (CCCs) and coefficients of variation. With regard to gait event detection, we found good overlaps for both systems. Compared to the marker-based motion analysis, OV achieved a strong to almost complete concordance regarding the sagittal measurement of cadence, gait variability, step time, stance time, step length, and double support (CCC ≥ 0.624), as well as regarding the frontal plane parameters of cadence, step time, stance time, and step width (CCC ≥ 0.805). For gait symmetry only, we found a moderate to weak correlation. These results support the CNN-based, markerless gait analysis system OV as an alternative to marker-based 3D motion capture systems for a broad variety of clinical applications.

## Full-text entities

- **Diseases:** musculoskeletal or neurodegenerative disorders (MESH:D019636), injury (MESH:D014947), Parkinson's disease (MESH:D010300), HD (MESH:D006816), neurological diseases (MESH:D020271), stroke (MESH:D020521), post-stroke hemiparesis (MESH:D010291), knee osteoarthritis (MESH:D020370), gait and movement disorders (MESH:D020234), musculoskeletal injuries (MESH:D009140), impairments of neuromuscular function (MESH:D009468), multiple sclerosis (MESH:D009103)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12609618/full.md

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Source: https://tomesphere.com/paper/PMC12609618