# Implementation, Validation and Clinical Testing of Oximetry Device for Microcirculation Assessment in Oral Tissue

**Authors:** Hojat Lotfi, Bibiana Falcão, Valentina Vassilenko

PMC · DOI: 10.3390/s25216604 · 2025-10-27

## TL;DR

This paper introduces a new oximetry device for non-invasive, real-time monitoring of oral tissue health by measuring oxygen saturation levels in the gums.

## Contribution

The novel pulse oximetry device uses reflective photoplethysmography for non-invasive gingival microcirculation assessment.

## Key findings

- The device's sensor probe design and calibration process were detailed and evaluated.
- Initial clinical measurements of gingival oxygen saturation were successfully obtained during oral rehabilitation consultations.

## Abstract

The recent rise in living standards has been accompanied by increased awareness and emphasis on oral health. Non-invasive assessment of gingival microcirculation and accurate evaluation of oxygen supply to oral tissues are critical for the early diagnosis of oral diseases. These factors also play a pivotal role in optimizing treatment planning and improving outcomes in dental implantology. In this study, we report the development and implementation of a novel pulse oximetry device based on reflective photoplethysmography technology, designed for non-invasive, real-time monitoring of gingival health through the measurement of oxygen saturation levels. A detailed description of the technology, including key aspects of sensor probe design, is provided, with particular emphasis on the calibration process and performance evaluation of the prototype. Furthermore, we present and discuss the first proof-of-concept gingival oxygen saturation measurements obtained in a clinical setting during oral rehabilitation consultations.

## Full-text entities

- **Diseases:** oral diseases (MESH:D009059)
- **Chemicals:** oxygen (MESH:D010100)

## Figures

11 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12609570/full.md

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Source: https://tomesphere.com/paper/PMC12609570