# Liver Abscess Caused by Klebsiella pneumoniae Originating from a Peri-Implant Abscess Following Dental Implant Surgery in a Patient with Diabetes: Case Report

**Authors:** Yu-Mi Lee

PMC · DOI: 10.3390/jcm14217634 · 2025-10-28

## TL;DR

A diabetic patient developed a rare liver abscess caused by bacteria from a dental implant infection.

## Contribution

This is the first reported case of a liver abscess caused by Klebsiella pneumoniae originating from a peri-implant abscess after dental implant surgery.

## Key findings

- A liver abscess and septic pneumonia caused by Klebsiella pneumoniae were diagnosed in a patient with a peri-implant abscess.
- The patient recovered with long-term antibiotic treatment alone, without needing drainage of the liver abscess.
- This case highlights the potential for systemic infections following dental implant surgery in vulnerable patients.

## Abstract

Backgroud: Liver abscesses caused by Klebsiella pneumoniae associated with dental implant surgery are rare. We report a case of liver abscess and septic pneumonia caused by K. pneumoniae in a patient who developed a peri-implant abscess following dental implant surgery. Methods: The 69-year-old male patient underwent a dental implant surgery on the upper right first premolar 10 days prior to admission, and the toothache and facial swelling worsened 5 days before admission. Results: One day before admission, a peri-implant abscess was diagnosed at a local dental clinic, and the patient underwent irrigation and drainage. On the day of admission, the patient visited our dental department and was admitted through the emergency room due to melena. The patient underwent further irrigation and drainage of the peri-implant abscess around the upper right first premolar. A liver abscess in segments 2/3 (3.1 cm) and septic pneumonia were diagnosed, and K. pneumoniae was identified in the blood and sputum cultures. The patient received antibiotic therapy (piperacillin-tazobactam, meropenem, and ceftriaxone, sequentially) without percutaneous drainage of the liver abscess due to the patient’s refusal and recovered without complications. The patient was administered ciprofloxacin for 5 months after discharge. One month after admission, the inflammatory maker returned to within reference range. The patient improved with long-term antibiotic treatment alone without drainage of the liver abscess. To our knowledge, this is the first report of a liver abscess caused by K. pneumoniae originating from a peri-implant abscess after dental implant surgery. Conclusions: Clinicians should be aware of the potential occurrence of liver abscesses caused by K. pneumoniae if signs of systemic infection persist along with peri-implant infection after dental implant surgery.

## Linked entities

- **Chemicals:** piperacillin-tazobactam (PubChem CID 461573), meropenem (PubChem CID 441130), ceftriaxone (PubChem CID 5479530), ciprofloxacin (PubChem CID 2764)
- **Diseases:** diabetes (MONDO:0005015)
- **Species:** Klebsiella pneumoniae (taxon 573)

## Full-text entities

- **Diseases:** melena (MESH:D008551), septic pneumonia (MESH:D011014), infection (MESH:D007239), Liver Abscess (MESH:D008100), toothache (MESH:D014098), Diabetes (MESH:D003920), facial swelling (MESH:D004487), inflammatory (MESH:D007249), Abscess (MESH:D000038)
- **Chemicals:** ceftriaxone (MESH:D002443), meropenem (MESH:D000077731), ciprofloxacin (MESH:D002939), piperacillin-tazobactam (MESH:D000077725)
- **Species:** Klebsiella pneumoniae (species) [taxon 573], Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12609200/full.md

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Source: https://tomesphere.com/paper/PMC12609200