# Effect of Antimicrobial Filler on Ethylene-Vinyl Acetate (EVA) Composites Property

**Authors:** Kamil Kwieciński, Marta Chrószcz-Porębska, Izabela Barszczewska-Rybarek, Jarosław Żmudzki, Anna Mertas, Sebastian Jurczyk, Paweł Popielski, Grzegorz Chladek

PMC · DOI: 10.3390/ma18214993 · Materials · 2025-10-31

## TL;DR

This paper studies how adding antimicrobial particles to EVA polymer improves its resistance to microbes without harming its other properties.

## Contribution

The novel contribution is demonstrating effective antimicrobial performance of SP-modified EVA composites with minimal impact on mechanical and thermal properties.

## Key findings

- EVA composites with 16 wt.% SP achieved 88% and 98% antimicrobial efficacy against Streptococcus mutans and Candida albicans.
- Cell viability remained above 70% in cytotoxicity tests with L-929 fibroblasts.
- Mechanical properties showed only minor changes with SP addition.

## Abstract

Ethylene–vinyl acetate (EVA) is a versatile polymer for applications in dental devices; however, its vulnerability to microbial colonization increases with long-term use. This study evaluates EVA composites modified with silver–sodium–hydrogen–zirconium phosphate (SP) particles, aimed at enhancing antimicrobial performance while preserving key functional properties. Composites containing 1–16 wt.% SP were prepared via solvent-based and mechanical compounding routes, with scanning electron microscopy confirming correct filler distribution across processing methods. Antimicrobial assays revealed a pronounced reduction in Streptococcus mutans and Candida albicans levels, reaching 88% and 98% antimicrobial efficacy, respectively, at 16 wt.% SP. Cytotoxicity testing with L-929 fibroblasts demonstrated maintained cell viability above the 70% threshold, confirming non-cytotoxicity. Mechanical characterization indicated marginal increases in hardness, slight tensile strength reduction at higher filler loadings, while other physicochemical and thermal analyses showed minimal impact on polymer performance. These findings indicate balanced antimicrobial activity with other biofunctional properties.

## Linked entities

- **Chemicals:** Ethylene–vinyl acetate (PubChem CID 32742), silver–sodium–hydrogen–zirconium phosphate (PubChem CID 165411904)

## Full-text entities

- **Diseases:** Cytotoxicity (MESH:D064420)
- **Chemicals:** zirconium phosphate (MESH:C027006), EVA (-), silver (MESH:D012834)
- **Species:** Candida albicans (species) [taxon 5476], Streptococcus mutans (species) [taxon 1309]
- **Cell lines:** L-929 — Mus musculus (Mouse), Spontaneously immortalized cell line (CVCL_AR58)

## Full text

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## Figures

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## References

120 references — full list in the complete paper: https://tomesphere.com/paper/PMC12608532/full.md

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Source: https://tomesphere.com/paper/PMC12608532