# Laparoscopy in the Surgical Management of Gynecological Cancer: A Comprehensive Update

**Authors:** Stamatios Petousis, Georgia Margioula-Siarkou, Chrysoula Margioula-Siarkou, Aristarchos Almperis, Frederic Guyon, Konstantinos Dinas

PMC · DOI: 10.3390/jcm14217614 · Journal of Clinical Medicine · 2025-10-27

## TL;DR

Laparoscopy is increasingly used in gynecological cancer surgery, with varying effectiveness across different cancer types.

## Contribution

This paper provides a comprehensive update on the evolving role of laparoscopy in the surgical management of gynecological cancers.

## Key findings

- Laparoscopy is the standard of care for endometrial cancer treatment and staging.
- Laparotomy is preferred over laparoscopy for cervical cancer due to worse survival outcomes reported in the LACC trial.
- Laparoscopy shows growing promise for early-stage ovarian cancer and is being explored for vulvar and breast cancer.

## Abstract

A laparoscopic approach has been incorporated into the surgical management of a great variety of gynecologic pathologies during the decades following the first description of the method. As knowledge and experience about the use of laparoscopy is accumulating, it is gradually being recognized as an oncologically safe and effective option for the surgical management of various types of gynecological cancer, and the indications for its applications are increasing, as controversial topics are resolved through research. Endometrial cancer is the gynecological malignancy with the most straightforward indications of laparoscopy in its treatment, since a minimally invasive approach is considered the standard of care for both the surgical treatment of early-stage disease and surgical staging through sentinel lymph node biopsy. The role of laparoscopy was significantly decreased in the surgical management of cervical cancer after the publication of the LACC trial which reported worse survival outcomes for patients treated with laparoscopy, and laparotomy has emerged as the preferred approach. However, laparoscopy can be acceptable for carefully selected cases of early-stage cervical cancer and has also been introduced as an effective method for the surgical staging of the disease. The use of laparoscopy in the diagnostic and therapeutic management of ovarian cancer is not fully established but is receiving growing attention, as increasing evidence supports the safety of this approach, especially in the treatment of early-stage disease, where it is considered an acceptable alternative approach to laparotomy. Finally, as laparoscopic advancements are continuously achieved, new indications for laparoscopy have been explored for both vulvar and breast cancer. Future research will identify and highlight new ways to further integrate laparoscopy into the diagnostic and therapeutic management of gynecological malignancies.

## Linked entities

- **Diseases:** endometrial cancer (MONDO:0002447), cervical cancer (MONDO:0002974), ovarian cancer (MONDO:0005140), vulvar cancer (MONDO:0001528), breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** ovarian cancer (MESH:D010051), Gynecological Cancer (MESH:D009369), vulvar and breast cancer (MESH:D001943), Endometrial cancer (MESH:D016889), gynecological malignancies (MESH:D005833), cervical cancer (MESH:D002583)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12608471/full.md

## References

138 references — full list in the complete paper: https://tomesphere.com/paper/PMC12608471/full.md

---
Source: https://tomesphere.com/paper/PMC12608471