# Rapid Hemi-Synthesis of Multifunctional Amphiphilic Derivatives Based on Polyphenolic Extractives: Surface Activity, Antioxidant and Antibacterial Properties

## TL;DR

This paper introduces a green method to create multifunctional plant-based compounds with surface, antioxidant, and antibacterial properties.

## Contribution

A novel green hemi-synthetic strategy to produce polyfunctional catechin derivatives with combined surface, antioxidant, and antibacterial properties.

## Key findings

- Bi-modular and tri-modular catechin derivatives show surface activity.
- The compounds exhibit strong radical scavenging and antibacterial activity against E. coli.

## Abstract

Growing concerns within the petrochemical industry regarding the security and sustainability of supply sources have prompted a search for alternative solutions. In this context, research focused on plant-based chemistry aims to develop molecules that can be transformed into new materials, biotechnological tools or industrial alternatives to fossil compounds. In addition, society and cosmetics companies are seeking to simplify formulations. Accordingly, we provide compounds that combine several functionalities, providing 2-in-1 or even 3-in-1 products. We present here a green hemi-synthetic strategy to obtain original polyfunctional derivatives of catechin by grafting fatty acid or fatty-alanine compounds. These bi-modular and tri-modular compounds exhibit surface activity and radical scavenging activity. They show significant antibacterial activity against E. coli as well.