# Uvular Branchial Cleft Cyst with Ectopic Parathyroid

## TL;DR

A rare case of a uvular cyst containing ectopic parathyroid tissue is reported, highlighting the need for detailed histopathological analysis.

## Contribution

This is the first documented case of a uvular branchial cleft cyst with ectopic parathyroid tissue.

## Key findings

- The cyst lining included non-keratinising squamous, ciliated columnar, and mucinous columnar epithelium.
- Ectopic parathyroid tissue was found within the cystic lumen.
- Uvular branchial cleft cysts with parathyroid tissue are previously unreported in the literature.

## Abstract

We hereby present a case of a 22-year-old female patient with a lesion on the right side of the uvula. Histopathological assessment identified a cystic lesion with a branching configuration. The cyst lining consisted of non-keratinising stratified squamous epithelium, ciliated columnar epithelium, and focal areas of mucinous columnar epithelium. Within the cystic lumen, a focus of ectopic parathyroid tissue was observed. Based on these findings, a final diagnosis of a uvular branchial cleft cyst containing ectopic parathyroid tissue was established. Pathological lesions of the uvula are rare, and cystic lesions typically correspond to epidermoid cysts. This case, therefore, represents the first documented occurrence of a uvular branchial cleft cyst containing ectopic parathyroid tissue, underscoring the importance of detailed histopathological and immunohistochemical evaluation in the assessment of even small, incidentally detected uvular lesions.