# Concurrent Systemic Lupus Erythematosus and Hashimoto's Thyroiditis: Clinical Patterns From Two Cases in Southwestern Nigeria

**Authors:** Gbenga Joshua Odunlami, Tajudin Adesegun Adetunji, Bolanle Aderonke Omotoso, Meveilleoux Soronuchi Frankpeace, Adeyemi Abiola Adefidipe, Francis Sunday Igwe, Airenakho Emorinken

PMC · DOI: 10.1155/crie/6623717 · Case Reports in Endocrinology · 2025-11-04

## TL;DR

This paper reports two cases from Nigeria where patients had both systemic lupus erythematosus and Hashimoto's thyroiditis, highlighting a rare autoimmune coexistence.

## Contribution

The study provides rare clinical insights into the coexistence of SLE and HT in sub-Saharan Africa.

## Key findings

- Two patients presented with coexisting systemic lupus erythematosus and Hashimoto's thyroiditis.
- This coexistence is rarely documented in sub-Saharan Africa.
- The findings emphasize the importance of considering autoimmune comorbidities in clinical practice.

## Abstract

Systemic lupus erythematosus (SLE) is an autoimmune, multisystemic connective tissue disease with a predilection for women in their reproductive age group. Hashimoto's thyroiditis (HT) is a chronic autoimmune-mediated inflammation of the thyroid gland. The coexistence of SLE with HT has been reported in the literature. However, this important coexistence has scarcely been reported in sub-Saharan Africa. Hence, we report two patients who presented with HT coexisting with SLE.

## Linked entities

- **Diseases:** Systemic lupus erythematosus (MONDO:0007915), Hashimoto's thyroiditis (MONDO:0007699)

## Full-text entities

- **Diseases:** autoimmune (MESH:D001327), inflammation of (MESH:D007249), autoimmune, multisystemic connective tissue disease (MESH:D003240), SLE (MESH:D008180), HT (MESH:D050031), thyroid gland (MESH:D013966)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12605862/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12605862/full.md

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Source: https://tomesphere.com/paper/PMC12605862