# Evaluation of post-laryngectomy dysphagia rehabilitation using High-Resolution impedance manometry: an exploratory study

**Authors:** Marise Neijman, Maarten J. A. van Alphen, Rob J.J.H. van Son, Martijn M. Stuiver, Frans J.M. Hilgers, Michiel W.M. van den Brekel, Lisette van der Molen

PMC · DOI: 10.1007/s00405-025-09642-z · European Archives of Oto-Rhino-Laryngology · 2025-10-03

## TL;DR

This study explores how High-Resolution Impedance Manometry can help understand swallowing difficulties in laryngectomy patients during rehabilitation.

## Contribution

The study introduces HRIM as a potential tool for evaluating swallowing biomechanics in alaryngeal patients.

## Key findings

- No significant changes were observed in pharyngeal contractile integrals or intra-bolus pressure after resistance-based training.
- Pharyngeal pressures and maximum admittance slightly decreased after training but increased during rest.
- HRIM provided insights but its clinical utility for this population remains uncertain.

## Abstract

This exploratory study analyzes High-Resolution Impedance Manometry (HRIM) data obtained during a phase II rehabilitation trial in laryngectomees at baseline (T0), after six-weeks of resistance-based training (T1), and after eight weeks of rest (T2), exploring its potential value in alaryngeal dysphagia research and clinical practice.

Pharyngeal HRIM was combined with videofluoroscopy to evaluate swallowing biomechanics in 17 laryngectomy patients. Parameters included Pharyngeal (Velo-, Meso-, and Hypopharyngeal) Contractile Integrals, Intra-Bolus Pressure, UES Relaxation Time, Maximum Admittance, and Integrated Relaxation Pressure.

No significant differences were found in the Pharyngeal Contractile Integrals, Intra-Bolus Pressure, Relaxation Time, Maximum Admittance, or Integrated Relaxation Pressure. However, pharyngeal pressures and Maximum Admittance slightly decreased from T0 to T1, and increased at T2 for all consistencies (thin, extremely thick, solid).

Alaryngeal resistance-based swallowing exercises lead to small, non-significant differences in pharyngeal pressures. HRIM provides valuable insights, but its application for this population remains uncertain.

The online version contains supplementary material available at 10.1007/s00405-025-09642-z.

## Full-text entities

- **Diseases:** dysphagia (MESH:D003680)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12605583/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12605583/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12605583/full.md

---
Source: https://tomesphere.com/paper/PMC12605583