# Research progress in vaccination during pregnancy

**Authors:** Jiao Zhang, Zhimin Li, Shiran Li, Pengfei Li, Jingxian Xie, Yong Yang

PMC · DOI: 10.3389/fimmu.2025.1687362 · Frontiers in Immunology · 2025-10-29

## TL;DR

This review discusses how vaccinating pregnant women protects both mothers and infants from infectious diseases.

## Contribution

The paper provides a global overview of vaccine effectiveness, safety, and recommendations during pregnancy.

## Key findings

- Vaccination during pregnancy reduces disease incidence and mortality in mothers and infants.
- Maternal antibodies transferred via the placenta offer protection to infants.
- Vaccination strategies and recommendations vary across countries.

## Abstract

Pregnant women and infants are more vulnerable to infectious diseases than the general population. Vaccination during pregnancy can protect not only mothers and fetuses from diseases but also safeguard infants through maternal antibodies transferred via the placenta. It stands as one of the most effective strategies to reduce the incidence and mortality of infectious diseases among pregnant women and infants. Globally, pregnancy vaccination strategies are increasingly diversified. This review discusses the effectiveness and safety of various vaccines for preventing infectious diseases during pregnancy, as well as vaccination recommendations for pregnant women across different countries.

## Full-text entities

- **Diseases:** infectious diseases (MESH:D003141)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12605263/full.md

## References

62 references — full list in the complete paper: https://tomesphere.com/paper/PMC12605263/full.md

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Source: https://tomesphere.com/paper/PMC12605263