# Dual Primary Gastric Adenocarcinoma and Diffuse Large B-Cell Lymphoma: A Unique Case With a Cascade of Rare Complications

## TL;DR

A 69-year-old patient had two rare stomach cancers and developed multiple severe complications, making treatment very complex.

## Contribution

This case highlights the rare co-occurrence of two primary gastrointestinal cancers and their cascade of uncommon complications.

## Key findings

- The patient had dual primary cancers: gastric adenocarcinoma and diffuse large B-cell lymphoma.
- Rare complications included duodenocolonic fistula, bowel perforation, pulmonary embolism, and multi-organ failure.
- The case demonstrates the exceptional complexity in managing such rare concurrent cancers and complications.

## Abstract

Concurrent presentation of two primary gastrointestinal cancers is extremely rare. We describe an unusual presentation of a 69-year-old patient without a significant past medical history, who was diagnosed simultaneously with diffuse large B-cell lymphoma and gastric adenocarcinoma. This case is distinguished by the development of severe, rarely reported complications such as duodenocolonic fistula, bowel perforation, pulmonary embolism, and multi-organ failure. The combination of those complications underscores the exceptional complexity of management.