# Ophthalmology Considerations in End-of-Life Care

**Authors:** Mendel Shloush, Akiva Eleff, Eric Eleff

PMC · DOI: 10.7759/cureus.94396 · Cureus · 2025-10-12

## TL;DR

This paper discusses how ophthalmologic treatments can improve quality of life for hospice patients, highlighting ethical and clinical considerations for various eye conditions.

## Contribution

The paper provides a comprehensive review of ophthalmologic interventions in hospice care, emphasizing their role in enhancing quality of life.

## Key findings

- Cataract surgery is cost-effective in hospice settings and improves vision and quality of life.
- ARMD treatment can sustain visual function within weeks despite requiring ongoing injections.
- Palliative glaucoma interventions can maintain comfort with minimal treatment burden.

## Abstract

Ophthalmologic interventions can significantly impact quality of life, even in the context of end-of-life care. This paper explores the ethical and clinical considerations for ophthalmologic treatments in hospice care, with a focus on cataract surgery, age-related macular degeneration (ARMD) therapy, retinal detachment (RD) repair, glaucoma, painful blind eye (PBE) management, benign and surface ocular tumors, and corneal or anterior segment diseases. A review of published literature and clinical precedent was conducted to assess the benefits, risks, and practical limitations of ophthalmologic procedures in hospice patients, with an emphasis on quality of life. Cataract surgery has been shown to be cost-effective in hospice settings, offering significant improvements in vision and overall quality of life. Treatment for ARMD, though requiring ongoing injections, can provide benefits within weeks and help sustain visual function. RD repair, while more complex, can substantially restore vision when appropriately managed. Palliative glaucoma interventions, including individualized target intraocular pressures and laser therapy, can minimize treatment burden while maintaining comfort. PBEs may be managed with retrobulbar chlorpromazine or alcohol injections, and enucleation or evisceration may be considered when pain persists. Benign or surface ocular tumors and corneal or anterior segment diseases can often be addressed with conservative, comfort-focused measures to reduce symptoms and preserve quality of life. Ophthalmologic procedures should be considered viable options in end-of-life care when clinically indicated, with careful ethical review. Restoration of vision contributes meaningfully to the quality of life and deserves thoughtful inclusion in care planning.

## Linked entities

- **Chemicals:** chlorpromazine (PubChem CID 2726)
- **Diseases:** age-related macular degeneration (MONDO:0005150), retinal detachment (MONDO:0008375), glaucoma (MONDO:0005041)

## Full-text entities

- **Diseases:** glaucoma (MESH:D005901), pain (MESH:D010146), PBE (MESH:D058447), Benign or surface ocular tumors (MESH:D009369), corneal or anterior segment diseases (MESH:C537775), Cataract (MESH:D002386), RD (MESH:D012163), ARMD (MESH:D008268)
- **Chemicals:** chlorpromazine (MESH:D002746), alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

66 references — full list in the complete paper: https://tomesphere.com/paper/PMC12604606/full.md

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Source: https://tomesphere.com/paper/PMC12604606