# Gene model for the ortholog of Gar1 in Drosophila willistoni

## TL;DR

This paper identifies the gene model for Gar1 in Drosophila willistoni and compares it to the related gene in Drosophila melanogaster.

## Contribution

The study establishes the orthology of Gar1 in D. willistoni and reveals structural differences in the gene.

## Key findings

- The Gar1 gene in D. willistoni has four coding exons, while D. melanogaster has three.
- Intron positions are not conserved between the two species.
- The Gar1 protein has a glycine-rich N-terminus and C-terminus.

## Abstract

The
Drosophila willistoni
feature with NCBI Gene ID 6651170 was established to be orthologous to
Drosophila melanogaster
gene
Gar1
. The
Gar1
protein contains the conserved domain H/ACA_rnp_Gar1/Naf1 (InterPro accession IPR007504) and the N-terminus and C-terminus of the protein are glycine-rich. There are major changes in the gene structure of the ortholog, Gar1-PA, between
D. melanogaster
and
D. willistoni
, which have three and four coding exons respectively. Notably, none of the intron positions are conserved between the two species.