# Pulsed Field Ablation in a Rheumatic Heart Disease Patient With Mechanical Mitral and Tricuspid Valves

**Authors:** Natee Deepan, Jervin Bisquera, Travis Fernandez, Alison Poppe, Pattara Rattanawong

PMC · DOI: 10.7759/cureus.94375 · Cureus · 2025-10-12

## TL;DR

This paper reports the first successful use of pulsed field ablation in a patient with mechanical heart valves and a history of surgery.

## Contribution

The study presents the first case of PFA in a patient with both mechanical mitral and tricuspid valves.

## Key findings

- Pulsed field ablation successfully isolated key cardiac regions without complications.
- The procedure avoided prosthetic structures using ICE and fluoroscopy guidance.
- PFA was feasible and safe in a patient with complex structural heart disease.

## Abstract

Pulsed field ablation (PFA) is a novel nonthermal modality for atrial fibrillation (AF) in patients with mechanical valves. We report the first successful PFA in a 44-year-old woman with both mechanical mitral and tricuspid valve replacements and a prior surgical maze procedure. Intracardiac echocardiography (ICE) and fluoroscopy-guided catheter navigation, avoiding prosthetic structures. Anatomical and voltage mapping revealed reconnection of prior surgical lines. PFA achieved isolation of the posterior wall, right pulmonary veins, inter-caval line, and cavotricuspid isthmus without complications. This case demonstrates the feasibility and safety of PFA in complex structural heart disease with dual mechanical valves.

## Linked entities

- **Diseases:** atrial fibrillation (MONDO:0004981), rheumatic heart disease (MONDO:0006955)

## Full-text entities

- **Diseases:** heart disease (MESH:D006331), Mitral (MESH:D008946), Rheumatic Heart Disease (MESH:D012214), Tricuspid Valves (MESH:D014262), AF (MESH:D001281)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12603598/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12603598/full.md

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Source: https://tomesphere.com/paper/PMC12603598