# Macular morphology after cataract surgery with and without primary posterior continuous curvilinear capsulorhexis

**Authors:** Chishan Kang, Kunxia Lin, Yulong Huang, Mengting Yu, Wenjie Wu

PMC · DOI: 10.3389/fmed.2025.1687460 · Frontiers in Medicine · 2025-10-28

## TL;DR

This study compares cataract surgery with and without a specific technique called PPCCC and finds no increased risk of eye complications.

## Contribution

The study demonstrates that PPCCC is a safe cataract surgery technique without increasing macular complications.

## Key findings

- PPCCC did not increase central retinal thickness or risk of cystoid macular edema compared to standard surgery.
- PPCCC prevented posterior vitreous detachment progression, unlike standard surgery.
- Visual acuity remained good in both groups after surgery.

## Abstract

To evaluate changes in macular morphology after cataract surgery with and without primary posterior continuous curvilinear capsulorhexis (PPCCC).

A prospective, intraindividual, randomized clinical trial was performed at Fuzhou University Affiliated Provincial Hospital, Fujian, China. A total of 130 eyes of 65 age-related cataract patients with normal macular morphology and function waiting for bilateral cataract surgery and intraocular lens (IOL) implantation were enrolled. Cataract surgery combined with PPCCC was performed in one eye, and routine cataract surgery in the fellow eye (NPCCC group). Optical coherence tomography (OCT) measurements were performed in all patients preoperatively and postoperatively on 1 day, 1 week, 1 month, and 3 months.

A total of 120 eyes of 60 patients were capable to complete scheduled follow-ups and analyzed in the study. There was no statistically significant difference between the PPCCC group and NPCCC group in terms of subfoveal central retinal thickness (CRT), central 1-mm subfield (CSF), average retinal thickness in the middle (1–3 mm) and outer (3–6 mm) rings (p > 0.05) at all timepoints after surgery. Three eyes developed cystoid macular edema (CME) 1-month post-surgery. One eye in the PPCCC group recovered in 2 weeks after topical treatment, while two in the NPCCC group took 8 weeks to recover. In the NPCCC group, PVD progressed in two eyes, one from stage 2 to 4, and another from stage 1 to 2. No PVD progression in the PPCCC group. The corrected distance visual acuity (CDVA) of all patients was logMAR 0.1 or better at the last visit.

Cataract surgery with combined manual PPCCC does not increase the risk of CME and PVD in patients. PPCCC is a safe cataract surgery technique.

## Linked entities

- **Diseases:** cataract (MONDO:0005129), cystoid macular edema (MONDO:0007935)

## Full-text entities

- **Diseases:** CME (MESH:D008269), Cataract (MESH:D002386)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12602534/full.md

## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12602534/full.md

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Source: https://tomesphere.com/paper/PMC12602534