# Revisiting the Model Human Processor: a neurophysiological investigation based on P300 and Bereitschaftspotential

**Authors:** Toshitaka Higashino, Naoki Wakamiya

PMC · DOI: 10.3389/fnhum.2025.1690746 · Frontiers in Human Neuroscience · 2025-10-28

## TL;DR

This study uses brainwave data to show that human information processing can follow two distinct neural pathways, one deliberate and one automatic.

## Contribution

The paper introduces a neurophysiologically validated dual-process model extending the Model Human Processor framework.

## Key findings

- A P300-absent subgroup among correct responses showed neural signatures similar to incorrect trials.
- The P300-absent subgroup had significantly shorter reaction times than the P300-present subgroup.
- The findings support a bifurcated model of information processing with deliberate and automatic pathways.

## Abstract

The Model Human Processor (MHP), while useful, lacks direct neurophysiological validation. This study aimed to validate and extend the MHP by analyzing P300 and Bereitschaftspotential (BP) brainwave components.

Our initial finding of qualitatively different neural signatures between correct and incorrect trials led to the hypothesis that the “correct” trial group is a mixture of different processing types. We tested this by segregating correct trials based on the presence or absence of the P300 component, which we reasoned is a key marker of the MHP’s conscious “Initiate Response” process.

We identified a P300-absent subgroup even among correct responses. This subgroup exhibited significantly shorter reaction times than its P300-present counterpart and showed a neural signature strikingly similar to that of incorrect trials, including a delayed negative peak in the BP.

These results suggest the human information processing pathway is not monolithic. We propose a new model that bifurcates after perception into either a “Deliberate Process” (P300-present), which aligns with the MHP, or a high-speed “Automatic Process” (P300-absent) that bypasses the MHP’s “Initiate Response” process. This work provides neurophysiological validation for the MHP and lends new neural support for dual-process theory.

## Full-text entities

- **Genes:** EP300 (EP300 lysine acetyltransferase) [NCBI Gene 2033] {aka KAT3B, MKHK2, RSTS2, p300}
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12602528/full.md

## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12602528/full.md

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Source: https://tomesphere.com/paper/PMC12602528