# Characteristics of moderate-to-severe chronic pain and its association with daily functional impairment among older outpatients in Vietnam

**Authors:** Thanh Xuan Nguyen, Thu Thi Hoai Nguyen, Huong Thi Thu Nguyen, Tam Ngoc Nguyen, Hong Trang Nguyen, Linh Huyen Vu Ha, Hoa Trung Dinh, Luc Viet Tran, Anh Trung Nguyen, Hoa Lan Nguyen, Robert Joel Goldberg, Janani Thillainadesan, Vasikaran Naganathan, Huyen Thi Thanh Vu

PMC · DOI: 10.1371/journal.pone.0335234 · PLOS One · 2025-11-10

## TL;DR

This study examines chronic pain in older Vietnamese outpatients and finds that moderate-to-severe pain is common and linked to greater daily functional impairment.

## Contribution

The study provides new insights into the characteristics and impact of chronic pain in older adults in Vietnam.

## Key findings

- Moderate-to-severe chronic pain was reported by many older outpatients in Vietnam.
- Pain in the knee-foot-leg region was the most common site of chronic pain.
- Moderate-to-severe pain was strongly associated with impaired daily and instrumental activities.

## Abstract

To describe the characteristics of moderate-to-severe chronic pain, and its association with daily functional decline among older individuals attending a large outpatient geriatric clinic in Hanoi, Vietnam.

A cross-sectional study was undertaken between November, 2019 and March, 2020. In-person structured interviews were conducted in 518 patients 60 years and older with chronic pain. Patient’s self-reported pain was categorised into two levels of mild (0–3), moderate to severe (4–10) pain based on a 0–10 scale.

The median age of the study sample was 69 years, women accounted for 74.1%.

The knee-foot-leg region was the most common site of chronic pain in both groups (39.5% in mild pain vs. 45.1% in moderate-to-severe pain. Participants experiencing moderate-to-severe pain were more likely to describe their pain as dull (65.5%) or burning (11.3%) and to report pain occurring independently of specific activities (48.7%), compared to those with mild pain (53.9%, 1.2%, and 32.4%, respectively). In a multivariable adjusted model, dependency in activities of daily living (OR: 3.73, 95% CI: 1.82–7.68) and dependency in instrumental activities of daily living (OR: 9.41, 95% CI: 3.94–22.5) were significantly associated with moderate-to-severe pain.

Moderate to severe chronic pain was reported in a high proportion of older Vietnamese outpatients and was associated with impaired daily functional impairment.

## Full-text entities

- **Diseases:** dependency (MESH:D019966), impaired daily functional impairment (MESH:D003072), pain (MESH:D010146), chronic pain (MESH:D059350)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

35 references — full list in the complete paper: https://tomesphere.com/paper/PMC12599909/full.md

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Source: https://tomesphere.com/paper/PMC12599909