# Midterm Results of Neocuspidization of the Aortic Valve with Ozaki Technique in Adults

**Authors:** Seguel S. Enrique, Reyes M. Rodrigo, González L. Roberto, Rubilar P. Héctor, Sepúlveda P. Camila, Barril M. Gustavo, Stockins L. Aleck

PMC · DOI: 10.21470/1678-9741-2024-0126 · Brazilian Journal of Cardiovascular Surgery · 2025-10-31

## TL;DR

This paper reports on the midterm outcomes of a new aortic valve replacement technique using a patient's own pericardium, showing promise for younger patients.

## Contribution

The study evaluates the neocuspidization technique's effectiveness and suitability in adult patients over a midterm period.

## Key findings

- The neocuspidization technique showed favorable midterm outcomes in 56 patients.
- The technique preserves native anatomy and avoids prosthetic materials, particularly beneficial for younger patients.
- Further research is needed to confirm long-term effectiveness and suitability for all patient types.

## Abstract

The neocuspidization technique using autologous pericardium
(AVNeo®) is a recent alternative for aortic valve
replacement in selected patients. Between 2019 and 2023, we applied it in 56
patients, evaluating surgical outcomes, survival, reintervention rates, and
clinical and echocardiographic results. We analyzed its advantages, patient
selection criteria, limitations, and management of bicuspid valves. We also
assessed whether it is suitable for all patients and discussed the midterm
outcomes observed. AVNeo® may offer a promising option,
especially for younger patients, by preserving native anatomy and avoiding
prosthetic materials, though long-term data and further research are still
needed.

## Full-text entities

- **Diseases:** bicuspid valves (MESH:D000082882)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12599831/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12599831/full.md

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Source: https://tomesphere.com/paper/PMC12599831