# Decentralized digital health ecosystems: a unified architecture for AI-enhanced medical record management

**Authors:** Harsha Kumar A., Preetham Venkatram C., Saran N., Disha Daniel, Praveen Joe I. R.

PMC · DOI: 10.3389/fdgth.2025.1685628 · Frontiers in Digital Health · 2025-10-27

## TL;DR

PolyMed is a decentralized health platform using blockchain and AI to improve EHR security, interoperability, and patient data control.

## Contribution

Introduces PolyMed, a unified decentralized architecture combining blockchain, AI, and edge computing for secure and patient-centric health data management.

## Key findings

- Empirical tests on Polygon Mainnet show sub-4-second transaction latencies and over 90% cost savings.
- The AI model achieves an AUC of 0.8543 and 80.33% accuracy in emergency detection on an imbalanced dataset.

## Abstract

Traditional Electronic Health Record (EHR) systems suffer from critical vulnerabilities in security, interoperability, and patient data control. This paper introduces PolyMed, a novel decentralized platform designed to address these challenges. PolyMed combines blockchain, Artificial Intelligence (AI), and edge computing into a synergistic architecture. It uses the Polygon blockchain for immutable record-keeping and a Decentralized Autonomous Organization (DAO) for transparent governance. Patient identity is secured through privacy-preserving zero-knowledge proofs (ZKPs) and anchored to non-transferable Soulbound Tokens (SBTs), granting users true sovereignty over their data. The platform also includes a Decentralized Finance (DeFi) module to improve healthcare accessibility. Empirical evaluations on the Polygon Mainnet confirm the system's viability, showing sub-4-second transaction latencies and over 90% cost savings compared to legacy systems. The integrated AI model, leveraging a LightGBM classifier on a rich set of engineered features, achieves an Area Under the Curve (AUC) of 0.8543 and an accuracy of 80.33% in emergency detection, demonstrating high reliability on a clinically relevant and imbalanced dataset. By aligning with global standards like General Data Protection Regulation (GDPR) and Health Insurance Portability and Accountability Act (HIPAA), PolyMed offers an integrated platform for patient-centric digital health management.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

15 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12598492/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12598492/full.md

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Source: https://tomesphere.com/paper/PMC12598492