# Changes in Neuropathic Pain Profiles by Dysesthesia-Matched Transcutaneous Electrical Nerve Stimulation: A Case Report

**Authors:** Takashi Hoei, Yuki Nishi, Seiji Etoh, Kentaro Kawamura, Megumi Shimodozono

PMC · DOI: 10.7759/cureus.94322 · Cureus · 2025-10-11

## TL;DR

A new TENS method tailored to a patient's pain perception significantly reduced neuropathic pain and dysesthesia in a cervical spinal stenosis case.

## Contribution

This is the first case report demonstrating DM-TENS effectiveness for pain profiles beyond dysesthesia.

## Key findings

- DM-TENS reduced throbbing pain from NRS 8 to 2 and improved pinch test accuracy.
- Adjusting DM-TENS for dysesthesia led to complete pain relief (NRS 0) and further improved pinch test results.
- The patient reported high satisfaction after treatment with DM-TENS synchronized to pain profiles.

## Abstract

Transcutaneous electrical nerve stimulation (TENS) is widely used to treat neuropathic pain because of its safety, but its therapeutic efficacy is limited. Dysesthesia-matched TENS (DM-TENS) is an innovative intervention that synchronizes TENS parameters with an individual patient's perception of dysesthesia. This case report describes a patient with cervical spinal stenosis whose throbbing pain evolved into dysesthesia. DM-TENS was synchronized with each neuropathic pain profile. Initially, the patient’s throbbing pain was rated 8 on a numerical rating scale (NRS), and the pinch force adjustment test (pinch test) showed a 2.58% mean error. DM-TENS synchronized to throbbing pain immediately reduced the NRS to 2 and the pinch test score to 2.06%. On postoperative day (POD) 13, the throbbing pain disappeared and evolved into dysesthesia (NRS 5, pinch test 2.41%). When the DM-TENS parameters were adjusted to match dysesthesia, immediate improvement was also achieved (NRS 0, pinch test 1.69%). By POD 20, the NRS for dysesthesia decreased to 3, and the patient reported high satisfaction. To our knowledge, this is the first case to demonstrate the effectiveness of DM-TENS synchronized with pain characteristics other than dysesthesia, highlighting the potential to broaden its clinical applications.

## Linked entities

- **Diseases:** cervical spinal stenosis (MONDO:0005965)

## Full-text entities

- **Diseases:** Neuropathic Pain (MESH:D009437), Dysesthesia (MESH:D010292), spinal stenosis (MESH:D013130), pain (MESH:D010146)
- **Chemicals:** DM (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12598372/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12598372/full.md

## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12598372/full.md

---
Source: https://tomesphere.com/paper/PMC12598372