Melioidosis Presenting as Retropharyngeal Abscess
Yong Wang Su, Aziah Ab Rani, Chee Yik Chang

Abstract
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Taxonomy
TopicsBurkholderia infections and melioidosis · Infections and bacterial resistance · Antibiotic Resistance in Bacteria
A 36-year-old man with underlying diabetes mellitus presented with a 2-week history of left-sided neck pain, fever, and dysphagia. Physical examination revealed a left intraoral lesion discharging pus. Incision and drainage of the lesion were performed, yielding approximately 10 cm^3^ of purulent material. A contrast-enhanced computed tomography (CT) scan of the neck revealed bilateral retropharyngeal collections (Figure 1). CT thorax and abdomen revealed no abnormalities. Pus culture grew Burkholderia pseudomallei, which was susceptible to ceftazidime, meropenem, and trimethoprim-sulfamethoxazole. Blood cultures were negative. The patient was treated with intravenous ceftazidime 2 g every 6 hours for 2 weeks, followed by oral trimethoprim-sulfamethoxazole for eradication therapy upon discharge.
Deep neck space infections are serious because of airway and vital structure involvement. Although usually polymicrobial, B. pseudomallei is a rare cause. Melioidosis is a tropical disease caused by *B. pseudomallei * ^(1)^. Retropharyngeal abscess caused by melioidosis is exceptionally rare. In addition to appropriate antimicrobial therapy, appropriate imaging and surgical drainage of the abscess is an important part of management ^(2)^.
Article Information
Author Contributions
All authors were involved in the acquisition of data, drafting the article, and final approval of the version to be submitted. Chee Yik Chang contributed to the conception and design of the study and supervision.
Conflicts of Interest
None
Consent Statement
Written consent has been obtained from the patient to publish the information, including the photographs.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Mohanty S, Sarkar S, Mishra B. Melioidosis of the head and neck: a case series from Eastern India. Infect Dis Rep. 2020;12(3):36-45.33138068 10.3390/idr 12030011 PMC 7768392 · doi ↗ · pubmed ↗
- 2Chang CY. Periorbital cellulitis and eyelid abscess as ocular manifestations of melioidosis: a report of three cases in Sarawak, Malaysian Borneo. ID Cases. 2020;19:e 00683.31908947 10.1016/j.idcr.2019.e 00683 PMC 6939086 · doi ↗ · pubmed ↗
