# A logistic regression-based nomogram model incorporating clinical, dietary, and nutritional data for predicting postoperative prognosis in elderly patients of grade A tertiary hospital

**Authors:** Yi-Qiang An, Jing Wei, Na Meng, Yan-Yan Xu, Zhi-Wen Li, Shi-Hong Zhao, Wen Tong

PMC · DOI: 10.3389/fnut.2025.1644583 · Frontiers in Nutrition · 2025-10-27

## TL;DR

This study creates a model to predict malnutrition risk in elderly patients after surgery using clinical and dietary data, aiming to improve postoperative care.

## Contribution

A novel logistic regression-based nomogram model integrating clinical, dietary, and nutritional factors for postoperative malnutrition prediction in elderly patients.

## Key findings

- The model achieved C-indices of 0.834 in training and 0.703 in validation sets.
- Key predictors included food types, cereal intake, protein intake, BMI, and serum markers.
- Calibration curves showed good model fit and ROC analysis confirmed predictive accuracy.

## Abstract

To develop and validate a logistic regression model predicting postoperative malnutrition risk in elderly patients using clinical, dietary, and nutritional data.

We analyzed 241 elderly patients (lung cancer lobectomy/esophageal cancer resection) admitted from January 2024 to December 2024. Participants were randomized 7:3 into training (n = 168) and validation (n = 73) sets. Prognostic factors were identified via univariate analysis and multivariate logistic regression to build a predictive model. Performance was assessed using C-index, calibration curves, and receiver operating characteristic (ROC) analysis.

Baseline characteristics were comparable between sets (P > 0.05). Multivariate analysis identified number of daily food types, cereal intake, high-quality protein intake, body mass index, serum albumin, and pre-albumin as malnutrition predictors (all P < 0.05). The model achieved C-indices of 0.834 (training set) and 0.703 (validation set). The area under the ROC curves were 0.834 (95% CI: 0.760–0.908) and 0.703 (95% CI: 0.539–0.866), respectively, with good calibration curve fit.

This validated model effectively predicts postoperative malnutrition risk in elderly surgical patients. Its visualization tools simplify complex nutritional assessment, offering a practical solution for resource-limited settings to improve postoperative care in grade A tertiary hospitals.

## Linked entities

- **Diseases:** lung cancer (MONDO:0005138), esophageal cancer (MONDO:0007576)

## Full-text entities

- **Genes:** ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}
- **Diseases:** malnutrition (MESH:D044342), esophageal cancer (MESH:D004938), lung cancer (MESH:D008175)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12597729/full.md

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Source: https://tomesphere.com/paper/PMC12597729