# A 44-Year-Old Man With a Solitary, Slowly Enlarging Mediastinal Lesion

**Authors:** Vasiliki Kolokotroni, Garyfallia Perlepe, Angeliki Cheva, Christoforos Foroulis, Konstantinos I. Gourgoulianis

PMC · DOI: 10.1016/j.chest.2025.04.037 · Chest · 2025-10-08

## TL;DR

A 44-year-old non-smoker with no symptoms was found to have a slowly growing mediastinal lesion during a routine life insurance radiograph.

## Contribution

The case highlights the incidental discovery of a mediastinal lesion in an asymptomatic individual.

## Key findings

- The patient had no symptoms or risk factors for mediastinal lesions.
- The lesion was detected incidentally during a routine radiograph for life insurance.
- Further investigation is needed to determine the nature of the lesion.

## Abstract

A 44-year-old man, who does not smoke, presented for investigation of a right mediastinum lesion as revealed on a routine radiograph that was performed as a requirement of his life insurance. The patient reported no associated symptoms. He did not report shortness of breath, cough, sputum, fever, chest pain, or hemoptysis. The remaining review of symptoms was also negative for issues such as muscle weakness, weight loss, night sweats, fatigue, skin rash, and visible, palpable, or painful lymphadenopathy. His medical history was unremarkable, and he did not receive any regular medication. The patient’s professional occupation was not related to special exposure and he did not report alcohol consumption, illicit drug use, or any recent travel.

## Full-text entities

- **Diseases:** shortness of breath (MESH:D004417), Mediastinal Lesion (MESH:D008477), mediastinum lesion (MESH:D008480), muscle weakness (MESH:D018908), cough (MESH:D003371), fatigue (MESH:D005221), hemoptysis (MESH:D006469), fever (MESH:D005334), skin rash (MESH:D005076), lymphadenopathy (MESH:D008206), weight loss (MESH:D015431), chest pain (MESH:D002637)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12597429/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12597429/full.md

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Source: https://tomesphere.com/paper/PMC12597429