# Dynamic improvement of tricuspid valve leaflets coaptation and tricuspid regurgitation without surgical treatment: a case report

**Authors:** Haruka Minami, Ayano Yoshida, Kyohei Onishi, Kosuke Fujita, Gaku Nakazawa

PMC · DOI: 10.1093/ehjcr/ytaf552 · European Heart Journal. Case Reports · 2025-10-23

## TL;DR

A high-risk patient's severe tricuspid regurgitation improved without surgery after treating heart conditions and arrhythmia.

## Contribution

Demonstrates non-surgical improvement of severe tricuspid regurgitation through comprehensive heart disease management.

## Key findings

- Tricuspid regurgitation severity improved from severe to moderate after transcatheter aortic valve implantation.
- Right atrium and right ventricle sizes reduced following treatment.
- Leaflet coaptation was observed after intervention despite initial absence.

## Abstract

Tricuspid regurgitation is a prevalent condition among patients with heart failure. Functional tricuspid regurgitation arises from multiple contributing factors, and tricuspid regurgitation severity is sensitive to changes in volume status. Importantly, significant tricuspid regurgitation is associated with adverse outcomes; therefore, tricuspid regurgitation management is crucial.

We describe the case of a 92-year-old man was diagnosed with decompensated heart failure with underlying reduced ejection fraction, multivessel coronary artery disease, low-flow low-gradient aortic stenosis, atrial flutter, and severe tricuspid regurgitation without leaflet coaptation. Owing to the high surgical risk, a minimally invasive treatment strategy was adopted. The patient underwent percutaneous coronary intervention of the left coronary artery, including the left main coronary artery, after which sinus rhythm was spontaneously restored. However, the severity of tricuspid regurgitation remained unchanged posttreatment. Thus, transcatheter aortic valve implantation was subsequently performed. Remarkably, echocardiography on the day after transcatheter aortic valve implantation revealed an improvement in tricuspid regurgitation severity from severe to moderate, with leaflet coaptation and size reduction of the right atrium and right ventricle.

This case highlights that severe tricuspid regurgitation, even without leaflet coaptation, can be improved through comprehensive management of ischaemia, valvular heart disease, and arrhythmia in the absence of surgical treatment. This treatment approach may offer clinical benefits to patients at high surgical risk.

## Linked entities

- **Diseases:** heart failure (MONDO:0005252), aortic stenosis (MONDO:0042981), atrial flutter (MONDO:0005310)

## Full-text entities

- **Diseases:** arrhythmia (MESH:D001145), coronary artery disease (MESH:D003324), valvular heart disease (MESH:D006349), aortic stenosis (MESH:D001024), Tricuspid regurgitation (MESH:D014262), heart failure (MESH:D006333), atrial flutter (MESH:D001282), ischaemia (MESH:D007511)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12596679/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12596679/full.md

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Source: https://tomesphere.com/paper/PMC12596679