# Novel PIK3CG compound heterozygous variants cause inactivated PI3Kγ syndrome presenting as necrotizing enterocolitis in a preterm infant

**Authors:** Wenting Zhang, Xiaoying Zhou, Bixia Zheng, Xinyi Yang, Yongcheng Ni, Dong Zhou, Chunli Wang

PMC · DOI: 10.1016/j.gendis.2025.101618 · Genes & Diseases · 2025-04-09

## Full-text entities

- **Genes:** PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) [NCBI Gene 5294] {aka IMD97, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma}
- **Diseases:** necrotizing enterocolitis (MESH:D020345), PI3Kgamma syndrome (MESH:D013577)

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