# CTHRC1 promotes the progression of clear cell renal cell carcinoma via the PI3K/AKT/GSK3β signaling pathway

**Authors:** Wei Xie, Zhouyong Fu, Thomas Skutella, Qing Jiang, Ronggui Zhang, Yuanfeng Zhang

PMC · DOI: 10.1016/j.gendis.2025.101688 · Genes & Diseases · 2025-05-13

## Full-text entities

- **Genes:** CTHRC1 (collagen triple helix repeat containing 1) [NCBI Gene 115908], GSK3B (glycogen synthase kinase 3 beta) [NCBI Gene 2932], PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta) [NCBI Gene 5291] {aka P110BETA, PI3K, PI3KBETA, PIK3C1}, AKT1 (AKT serine/threonine kinase 1) [NCBI Gene 207] {aka AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA}
- **Diseases:** clear cell renal cell carcinoma (MESH:D002292)

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## References

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Source: https://tomesphere.com/paper/PMC12596567