# Acute nicotine poisoning in a 2-year-old child - A case report of a near-death event

**Authors:** Mohd Shaiful Ehsan Shalihin, Sakinah Md Rifin, Nur Izzati Binti Mohd Sabri

PMC · DOI: 10.51866/cr.532 · Malaysian Family Physician : the Official Journal of the Academy of Family Physicians of Malaysia · 2025-10-18

## TL;DR

A 2-year-old child nearly died from acute nicotine poisoning after ingesting liquid nicotine at home, highlighting the dangers of vaping to children.

## Contribution

This case report emphasizes the severe risks of nicotine exposure to young children due to parental vaping habits.

## Key findings

- A 2-year-old child developed acute respiratory failure after ingesting liquid nicotine.
- The child experienced multiple seizures and required intensive care.
- The case underscores the need for stricter regulations on nicotine products to protect children.

## Abstract

Acute nicotine poisoning is a devastating condition that occurs when there is an excessive intake of nicotine, a toxic alkaloid found in tobacco products, mainly e-cigarettes. It impairs respiratory and neurological functioning due to its massive inflammatory effect. It is mainly related to vaping activity. Most smokers know about smoking’s adverse effects and implications. However, public awareness is still poor, and a majority are unable to quit the trending vaping addiction. Nevertheless, the potential severity of its toxicity to a growing child both in the short and long term is of critical concern, especially in cases of accidental direct ingestion. We report the case of a 2-year-old child who presented with acute respiratory failure secondary to liquid nicotine ingestion at home. The child was first seen by the medical team at primary care and required urgent intubation and paediatric intensive care unit admission. Her condition was complicated with several episodes of seizure requiring close monitoring. This case highlights that despite ignorance of adults on the danger of vaping, significant harm can still occur among children at home when parents engage in vaping. Although adults may take certain precautions, their harmful habits can indirectly and directly affect children, making the risk unavoidable. This serves as an urgent call for the government to strictly ban nicotine products and enact corresponding legislation immediately.

## Linked entities

- **Chemicals:** nicotine (PubChem CID 942)
- **Diseases:** acute respiratory failure (MONDO:0001208)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** toxicity (MESH:D064420), nicotine (MESH:D014029), death (MESH:D003643), respiratory failure (MESH:D012131), inflammatory (MESH:D007249), addiction (MESH:D019966), seizure (MESH:D012640), poisoning (MESH:D011041)
- **Chemicals:** nicotine (MESH:D009538)
- **Species:** Nicotiana tabacum (American tobacco, species) [taxon 4097]

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12596154/full.md

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Source: https://tomesphere.com/paper/PMC12596154