# Water-Jet Assisted Liposuction in Lipedema: Which Cannula is the Safest?

**Authors:** Marie-Luise Aitzetmüller-Klietz, Jonah Berg, Tobias Hirsch, Matthias Aitzetmüller-Klietz

PMC · DOI: 10.1093/asjof/ojaf120 · Aesthetic Surgery Journal. Open Forum · 2025-09-26

## TL;DR

This study compares different cannulas used in water-jet assisted liposuction for lipedema to determine which is safest and most efficient.

## Contribution

The study provides empirical data on complication rates and efficiency of different cannula designs in lipedema patients.

## Key findings

- 8-port cannulas aspirated more fat faster but caused higher hemoglobin loss.
- Cannula diameter had less impact on aspiration speed and hemoglobin loss.
- Ø4.8 mm cannulas had more wound-healing issues compared to Ø3.8 mm ones.

## Abstract

Liposuction in lipedema is a safe and effective treatment, but there currently are no studies analyzing the individual complications of water-jet-assisted liposuction in lipedema or the impact of the cannula's design.

The aim of the authors of this study is to answer the question which WAL cannula is the safest in lipedema patients and provide practitioners with the data they need to make an informed decision about the cannula they choose.

The authors retrospectively analyzed complications and their underlying risk factors in 117 patients across 243 cases. Groups were formed by diameter (Ø) and number of ports of the used cannulas. Unpaired t-tests, Fisher's exact tests, and χ2 tests were used to analyze the patients’ characteristics for the complication rates across the cannulas.

Cannulas with 8 ports showed statistically significantly higher hemoglobin loss (P = .011), shorter incision-to-suture time (P = .023), and higher volume of aspirated fat (P < .001). The same results occurred when comparing the Ø3.8 mm cannulas that differ in the number of ports (4 vs 8 ports). The Ø4.8 mm group showed a significantly increased rate of wound-healing disorders compared with the Ø3.8 mm group (P = .041) and a statistically significantly higher aspirated fat volume (P = .014).

No specific cannula showed superior safety in terms of complication rates. However, 8-port cannulas facilitated a faster aspiration of large volumes and reduced the incision-to-suture time compared with 4-port cannulas. This benefit was accompanied by a greater loss of hemoglobin. In contrast, cannula diameter played a less significant role in aspiration speed and did not increase the hemoglobin loss.

## Linked entities

- **Diseases:** lipedema (MONDO:0013577)

## Full-text entities

- **Diseases:** Lipedema (MESH:D065134)
- **Chemicals:** Water (MESH:D014867)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12596102/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12596102/full.md

## References

39 references — full list in the complete paper: https://tomesphere.com/paper/PMC12596102/full.md

---
Source: https://tomesphere.com/paper/PMC12596102