# Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project

**Authors:** Vishal Avinashi, Milli Gupta, Beth A. Payne, Haneen Amhaz, Alisha T. Temirova, Waqqas Afif, Dhandapani Ashok, Janice Barkey, David Burnett, Jonathan W. Bush, Scott Cameron, Stuart Carr, Dina El Demellawy, Stephanie Erdle, Hien Q. Huynh, Jennifer Griffin, Samir C. Grover, Kelly Grzywacz, Samira Jeimy, Hin Hin Ko, Gina Lacuesta, Margaret Marcon, Serge Mayrand, Harrison Petropolis, David Rodrigues, Mary Sherlock, Christine Song, Natacha Tardio, Timothy K. Vander Leek, Meagan Vurzinger, Brock A. Williams, Ted Xenodemetropoulos, Christopher Ma, Edmond S. Chan

PMC · DOI: 10.1186/s13223-025-00993-0 · Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology · 2025-11-07

## TL;DR

This paper provides the first Canadian consensus recommendations for diagnosing and managing eosinophilic esophagitis in both adults and children.

## Contribution

The study introduces the first evidence and expert opinion-based Canadian guidelines for eosinophilic esophagitis care.

## Key findings

- Thirty-eight recommendations were developed through a Delphi consensus process involving 31 Canadian experts.
- The guidelines cover three areas: definition, diagnosis, and management of eosinophilic esophagitis.
- A table of research gaps was identified to guide future studies on EoE in Canada.

## Abstract

Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus that effects both pediatrics and adult patients in Canada and is increasing in prevalence. No Canadian focused best practice recommendations currently exist to guide clinical practice.

The study used a modified Delphi technique to develop evidence and expert opinion-based recommendations for providing care for patients with EoE. The Delphi process consisted of 3 rounds of quantitative surveys and qualitative consensus meetings. Experts were included in the Delphi if they had experience caring for EoE patients in Canada within one of the following professional groups: allergist, adult gastroenterologists, pathologists, pediatric gastroenterologists, and dieticians.

Delphi rounds were completed between May 1, 2024, and June 30, 2024. A total of 31 experts in EoE care from across Canada were recruited to participate in the Delphi consensus process. All participants completed all three rounds of Delphi surveys. The final statement includes 38 recommendations for the care of patients with EoE organized into three sections: definition, diagnosis, and management. A Table of research gaps is provided to stimulate further knowledge development on this topic.

This consensus statement includes actionable recommendations to support quality care of patients with EoE at any age across Canada. We encourage EoE centers in Canada to come together in a multi-disciplinary form to not only provide clinical care but also do much needed research on Canadian specific topics and gaps in EoE care.

The online version contains supplementary material available at 10.1186/s13223-025-00993-0.

## Linked entities

- **Diseases:** eosinophilic esophagitis (MONDO:0005361)

## Full-text entities

- **Diseases:** inflammatory disease of the esophagus (MESH:D004938), EoE (MESH:D057765)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12595650/full.md

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Source: https://tomesphere.com/paper/PMC12595650