# Robot-assisted laparoscopic resection of giant left renal angiomyolipoma and multiple left retroperitoneal angiomyolipomas: a case report of lymphangioleiomyomatosis

**Authors:** Jianjia Huang, Junjie Bai, Jun Lin, Xiaoyan Li, Jianhui Chen

PMC · DOI: 10.1186/s12894-025-01924-2 · BMC Urology · 2025-11-07

## TL;DR

A young woman with large kidney tumors underwent robot-assisted surgery, successfully preserving her kidney and later recovering from a related lung condition.

## Contribution

Demonstrates the feasibility and effectiveness of robot-assisted laparoscopic nephron-sparing surgery for complex multifocal renal angiomyolipoma.

## Key findings

- Robot-assisted laparoscopic surgery successfully removed a giant left renal angiomyolipoma while preserving kidney function.
- The patient was later diagnosed with sporadic lymphangioleiomyomatosis following postoperative respiratory symptoms.
- Treatment with sirolimus and symptomatic care led to recovery without disease recurrence during follow-up.

## Abstract

We report a young female patient with a giant left renal angiomyolipoma (AML) and multiple left retroperitoneal AML. After undergoing robotic-assisted laparoscopic surgery, the tumor was successfully removed cleanly while preserving the normal renal unit. On the fourth day after surgery, she developed respiratory symptoms, including chylothorax, and was diagnosed with sporadic lymphangioleiomyomatosis (LAM) combined with multiple AML. After receiving sirolimus and symptomatic treatment, the patient recovered and had no recurrence of the disease during the follow-up period. This case demonstrates the significant application of robot-assisted laparoscopic nephron-sparing surgery in the treatment of a giant renal angiomyolipoma (14.0 cm in diameter), highlighting its feasibility and effectiveness in managing complex multifocal disease while preserving renal function.

## Linked entities

- **Chemicals:** sirolimus (PubChem CID 5284616)
- **Diseases:** angiomyolipoma (MONDO:0002603), lymphangioleiomyomatosis (MONDO:0006277)

## Full-text entities

- **Diseases:** AML (MESH:D018207), chylothorax (MESH:D002916), tumor (MESH:D009369), LAM (MESH:D018192)
- **Chemicals:** sirolimus (MESH:D020123)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12595607/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12595607/full.md

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Source: https://tomesphere.com/paper/PMC12595607