Ce -NeRV3D - a C. elegans Neuron RNA-seq Visualization tool in 3D

TL;DR

Ce-NeRV3D is a 3D visualization tool for exploring gene expression in the C. elegans nervous system using RNA-seq data.

Contribution

The novel contribution is a Blender plugin that integrates transcriptomic data with 3D neural anatomy for interactive exploration.

Findings

Ce-NeRV3D allows visualization of gene expression patterns in the 3D nervous system of C. elegans.

The tool supports overlaying single-cell RNA sequencing data onto anatomical structures.

Users can explore spatial gene co-expression with customizable color mapping.

Abstract

Caenorhabditis elegans

provides a tractable model for neural circuit studies, with complete connectomes and single-cell transcriptomic atlases available. Here, we present
Ce
-NeRV3D (

C. elegans

Neuron RNA-seq Visualization tool in 3D), a Blender plug-in that allows visualizing the expression patterns of an unlimited number of genes within the worm's 3D nervous system. The tool enables users to explore the spatial distribution of gene co-expression with customizable color mapping, overlay single-cell RNA sequencing data onto the anatomical structure, and interactively examine transcriptomic datasets in the context of detailed neural anatomy.

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