# Ligand-directed covalent labelling of adenosine receptors

**Authors:** Chloe Keduan Li, Karen Joan Gregory, Manuela Jörg

PMC · DOI: 10.1007/s11302-025-10073-y · 2025-02-24

## Full-text entities

- **Genes:** CA2 (carbonic anhydrase 2) [NCBI Gene 760] {aka CA-II, CAC, CAII, Car2, HEL-76, HEL-S-282}, ADORA2A (adenosine A2a receptor) [NCBI Gene 135] {aka A2aR, ADORA2, RDC8}, FKBP1A (FKBP prolyl isomerase 1A) [NCBI Gene 2280] {aka FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2}, RIEG2 (Rieger syndrome 2) [NCBI Gene 6012] {aka ARS, RGS2}
- **Diseases:** cardiovascular diseases (MESH:D002318), Parkinson's disease (MESH:D010300), schizophrenia (MESH:D012559), neurodegenerative disorders (MESH:D019636), cancers (MESH:D009369), cytotoxicity (MESH:D064420)
- **Chemicals:** sulphonamide (MESH:D013449), cAMP (MESH:D000242), tyrosines (MESH:D014443), copper (MESH:D003300), ZM241385 (MESH:C097270), lysine (MESH:D008239), fluorine (MESH:D005461), 5'-p-fluorosulfonyl benzoyl adenosine (MESH:C010959), water (MESH:D014867), 1,3-difluorobenzene (MESH:C079487), SDS (MESH:D012967), LUF7445 (MESH:C000626539), amino acid (MESH:D000596), azide (MESH:D001386), alkyne (MESH:D000480), Adenosine (MESH:D000241), cysteines (MESH:D003545), cyano-substituted NASA (-), biotin (MESH:D001710), sulfate (MESH:D013431)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116], Homo sapiens (human, species) [taxon 9606]
- **Mutations:** A1 adenosine, A2A

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12595162/full.md

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Source: https://tomesphere.com/paper/PMC12595162