Silk-Derived Peptide Modification to Polymers Improves the Miscibility of Composite Materials with Silk Fibroin
Yuri Matsumoto, Shota Akioka, Yasumoto Nakazawa
TL;DR
Modifying polymers with silk-derived peptides improves the compatibility and strength of silk fibroin composite materials.
Contribution
A novel method using silk fibroin motif peptides to enhance polymer composite miscibility and physical properties.
Findings
Peptide modification improves thermal properties and molecular mobility in composites.
Physical properties of composites correlate with molecular structure after modification.
The method offers an innovative solution to the miscibility issue in SF/polymer composites.
Abstract
Silk fibroin (SF)/polymer composite materials typically exhibit degraded material strength because of their low miscibility. Therefore, we hypothesize that compatibility issues can be solved by modifying SF primary structure motif peptides into polymers. Physical property and structural analyses are performed on fabricated SF/polymer composites. These results suggest that miscibility is improved by modifying the peptide in terms of its thermal properties and molecular mobility. Further, physical properties are improved by peptide modification and are correlated with molecular structure. These findings indicate that SF primary structure motif peptide modification is an innovative technology that can solve the miscibility issue of SF/polymer composite materials.
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Taxonomy
TopicsSilk-based biomaterials and applications · Antimicrobial Peptides and Activities · Electrospun Nanofibers in Biomedical Applications