# CA turns 75: Looking at the future but never forgetting the roots

**Authors:** Don S. Dizon, Sumanta Kumar Pal, Banu E. Symington, Razelle Kurzrock, Arif H. Kamal, Christina M. Annunziata, Shanthi Sivendran, Ahmedin Jemal, William L. Dahut

PMC · DOI: 10.3322/caac.70040 · Ca · 2025-11-03

## Full-text entities

- **Genes:** TXK (TXK tyrosine kinase) [NCBI Gene 7294] {aka BTKL, PSCTK5, PTK4, RLK, TKL}, ERBB2 (erb-b2 receptor tyrosine kinase 2) [NCBI Gene 2064] {aka CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19}
- **Diseases:** Philadelphia chromosome (MESH:D010677), LUNG (MESH:D008175), USHERING (MESH:D052245), Cancer (MESH:D009369), ADULTS (MESH:C538052), breast cancer (MESH:D001943), CRC (MESH:D015179), positive (MESH:D000377), death (MESH:D003643), FACTOR (MESH:D005171), cervical cancer (MESH:D002583), -WORLD (MESH:D016773), chronic myelogenous leukemia (MESH:D015464)
- **Chemicals:** trastuzumab (MESH:D000068878)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12593277/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12593277/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12593277/full.md

---
Source: https://tomesphere.com/paper/PMC12593277