# Mifepristone Access Through Community Pharmacies When Regulated as a Routine Prescription Medication

**Authors:** Elizabeth Nethery, Catherine Xu, Carissa S. Y. Chan, Mary Helmer-Smith, Andrea Stucchi, Dawn Mooney, Enav Z. Zusman, Sheila Dunn, Robert Pammett, Wendy V. Norman, Giuliana Guarna, Michael R. Law, Laura Schummers

PMC · DOI: 10.1001/jamanetworkopen.2025.42096 · JAMA Network Open · 2025-11-06

## TL;DR

This study examines how accessible mifepristone is at community pharmacies in British Columbia when it is treated as a regular prescription medication.

## Contribution

The study provides new insights into the geographic and operational accessibility of mifepristone for medication abortion in Canada.

## Key findings

- 66% of pharmacies could dispense mifepristone within 3 days, and 12% referred to another pharmacy.
- 99% of reproductive-aged females in BC lived within a 15-minute drive of a dispensing pharmacy.
- 23% of pharmacies neither dispensed mifepristone nor provided a referral, highlighting access gaps.

## Abstract

This cross-sectional study quantifies the availability of mifepristone within 3 calendar days at community pharmacies across British Columbia, Canada.

What proportion of community pharmacies dispense mifepristone within 3 calendar days when mifepristone is regulated as a routine prescription medication?

This cross-sectional study using a mystery caller survey of 1460 pharmacies in British Columbia, Canada, found that 66% of pharmacies could dispense mifepristone within 3 days and 12% referred to another pharmacy that could.

These findings suggest that when medication abortion is available as a routine health service and mifepristone is regulated as a routine prescription, pharmacists play a key role in providing geographically distributed access to medication abortion; access could be improved through policies and initiatives that enhance and support pharmacist referral networks.

The mifepristone-misoprostol medication abortion regimen became available in Canada as a normally prescribed medication, without restrictions, in 2017. Despite rapid uptake, patients have reported difficulty accessing this time-sensitive medication.

To quantify mifepristone availability within 3 calendar days at community pharmacies.

This population-based, cross-sectional study using a mystery caller survey was conducted from July to August 2024 at community pharmacies in British Columbia (BC), Canada.

Surveyor posing as a patient with a prescription for mifepristone who requests to pick up the medication within 3 calendar days. For nondispensing pharmacies (ie, unable to dispense within 3 days), surveyors requested a referral to a dispensing pharmacy.

Proportion of pharmacies that could dispense mifepristone or provide a valid referral to a dispensing pharmacy; proportion of reproductive-aged (15-49 years) female population residing within 15-minute walking and 15-, 30-, and 60-minute driving times of a dispensing pharmacy, and proportion of the population with poor local availability (<50% of available pharmacies dispense mifepristone).

Among 1460 of 1482 community pharmacies, 962 (66%) could dispense mifepristone within 3 days and 169 (12%) provided a valid referral. Only one-third of nondispensing pharmacies (169 of 498 pharmacies [34%]) provided a valid referral to a dispensing pharmacy; 329 pharmacies (23%) neither dispensed within 3 days nor provided a valid referral. Almost all reproductive-aged females (1 095 915 of 1 110 218 females [99%]) in BC lived within a 15-minute drive of a mifepristone-dispensing pharmacy. Urban pharmacies were more likely to be nondispensing and nonreferring (relative risk [RR], 1.78; 95% CI, 1.19-2.80) and less likely to offer same-day dispensing (RR, 0.39; 95% CI, 0.30-0.51) compared with rural pharmacies. Populations in areas with the most residential instability (RR, 1.41; 95% CI, 1.19-1.67) or greater ethnocultural diversity (RR, 1.36; 95% CI, 1.15-1.61) had poorer local availability of mifepristone-dispensing pharmacies.

This cross-sectional study found 99% of reproductive-aged BC females lived within a 15-minute drive of a mifepristone-dispensing pharmacy; however, despite relatively good geographic coverage and mifepristone being available as a routine prescription, 23% of pharmacies neither dispensed within 3 days nor provided a valid referral, putting the onus on patients to identify a dispensing pharmacy. These findings may inform policy and initiatives to enhance pharmacist referral networks and improve mifepristone access, as well as service planning for international jurisdictions considering a similar medication abortion framework.

## Linked entities

- **Chemicals:** mifepristone (PubChem CID 4196), misoprostol (PubChem CID 5282381)

## Full-text entities

- **Chemicals:** Mifepristone (MESH:D015735), misoprostol (MESH:D016595)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

58 references — full list in the complete paper: https://tomesphere.com/paper/PMC12593126/full.md

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Source: https://tomesphere.com/paper/PMC12593126